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NCT07088601: OOPS
Efficacy of Oral Ondansetron Strips on Prevention of Post-Spinal Shivering
Phase 4 trial testing Oral ondansetron strips in Post-Spinal Shivering in 50 participants. Not yet recruiting.
29 December 2025
Quick facts
| Lead sponsor | Cairo University |
|---|---|
| Phase | Phase 4 |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | prevention |
| Enrollment | 50 |
| Start date | 10 August 2025 |
| Primary completion | 29 December 2025 |
| Estimated completion | 29 December 2025 |
Drugs / interventions tested
- Oral ondansetron strips — full drug profile →
- Placebo (oral peppermint strip)
Conditions studied
- Post-Spinal Shivering — all drugs for Post-Spinal Shivering →
Sponsor
Cairo University
Who can join
Adults 18 to 65, any sex, with Post-Spinal Shivering. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study aims to investigate the efficacy of oral ondansetron film strips on the incidence of post-spinal shivering in patients undergoing surgeries using spinal anesthesia at Kasr Alainy hospitals, Cairo University. This prospective, double-blinded, randomized controlled study will be conducted on 50 patients aged from 18 to 65 years of both sexes with ASA I, II who are scheduled for elective surgical procedures under spinal anesthesia in the lower half of the body such as orthopedic, urological, or general surgeries. Patients will be divided into two equal groups: Group (O) will receive oral ondansetron in the form of an oral soluble film 4 mg strip immediately before insertion of IV cannula and group (C) will receive a placebo in the form of an oral peppermint strip immediately before insertion of the IV cannula.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07088601
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07088601 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Cairo University
- Last refreshed: 30 July 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07088601.
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