NCT07088510 is a NA clinical trial of Hysteroscopic resection in Miscarriage in First Trimester, sponsored by University Hospitals Cleveland Medical Center.

Who is sponsoring NCT07088510?

NCT07088510 is sponsored by University Hospitals Cleveland Medical Center.

What drugs are being tested in NCT07088510?

Interventions in NCT07088510: Hysteroscopic resection, Manual Vacuum Aspiration.

What condition does NCT07088510 study?

NCT07088510 studies Miscarriage in First Trimester.

Is NCT07088510 still recruiting?

NCT07088510 is currently recruiting now. Last updated 30 July 2025.

Last reviewed 2025-07-30 · How we verify

NCT07088510

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Hysteroscopic Resection Versus Manual Vacuum Aspiration for Early Pregnancy

Recruiting now NA Last updated 30 July 2025

What this trial tests

NA trial testing Hysteroscopic resection in Miscarriage in First Trimester in 80 participants. Currently enrolling.

Timeline

31 March 2025

Primary endpoint
30 April 2027

30 April 2028

Quick facts

Lead sponsor	University Hospitals Cleveland Medical Center
Phase	NA
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	80
Start date	31 March 2025
Primary completion	30 April 2027
Estimated completion	30 April 2028
Sites	1 location across United States

Drugs / interventions tested

Hysteroscopic resection
Manual Vacuum Aspiration

Conditions studied

Miscarriage in First Trimester — all drugs for Miscarriage in First Trimester →

Sponsor

University Hospitals Cleveland Medical Center

Who can join

Adults 18 to 55, female only, with Miscarriage in First Trimester. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Early pregnancy loss happens when a pregnancy that is not developing properly is found on an ultrasound before 12 weeks and 6 days. This type of loss occurs in about 10% of pregnancies. There are three main ways to treat this: waiting for it to pass naturally, using medication, or having surgery. Surgery is the most effective, working 99% of the time, compared to waiting (80% effective in 8 weeks) and medication (71-84% effective). Currently, surgery involves dilation of the cervix and curettage (removal of pregnancy tissue) with suction provided either from a manual hand-held pump or a machine. For the purposes of this study, a manual vacuum aspirator (or hand-held pump) will be used with ultrasound guidance. There is also another method called hysteroscopic resection, where the doctor uses a special camera to directly see and remove any pregnancy tissue from your uterus. Patients often want the quickest way to resolve the pregnancy loss, and physicians are unsure which surgical method is the best. It's also unclear if one type of surgery causes less scar tissue inside the uterus, affects the ability to test the tissue for genetic issues, or impacts how soon a patient can start fertility treatments again. This study aims to find out if hysteroscopic resection provides faster resolution and creates less scar tissue compared to the manual vacuum aspiration.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other recruiting trials for Miscarriage in First Trimester

Currently open trials in the same condition.

NCT07160855 — Letrozole Plus Misoprostol Versus Misoprostol Alone for Treating Women With Missed Miscarriage · Phase 4 · recruiting
NCT06581692 — Non-invasive Monitoring of Miscarriage · recruiting
NCT06452719 — Letrozole and Misoprostol for Early Pregnancy Loss Management · Phase 2 · recruiting
NCT06384144 — Machine Learning Miscarriage Management Clinical Decision Support Tool Study · recruiting
NCT05516810 — The Accuracy of Ultrasound Diagnosis of Hydatidiform Moles · active not recruiting

Other University Hospitals Cleveland Medical Center trials

Trials by the same sponsor.

NCT06997198 — Deutetrabenazine Treatment for Tardive Dyskinesia in Intellectual/Developmental Disabilities · Phase 4 · not yet recruiting
NCT07379814 — Rectus Abdominis Detrusor Myoplasty for Urinary Retention · not yet recruiting
NCT07499648 — Baby Steps to Care · NA · not yet recruiting
NCT07497737 — OMT for Adhesive Capsulitis · Phase 4 · not yet recruiting
NCT06523166 — Direct Comparison of Cardiac CT With TEE to Evaluate Watchman FLX LAA Occluder Device Characteristics · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT07088510 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University Hospitals Cleveland Medical Center
Last refreshed: 30 July 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07088510.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing