Last reviewed · How we verify
NCT07087600
Immediate Effects of Automatic Lateralization in Critically Ill Patients
NA trial testing Automatic lateralization therapy in Intensive Care Units in 10 participants. Completed in 30 October 2025.
30 September 2025
Quick facts
| Lead sponsor | University of Pernambuco |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 10 |
| Start date | 14 August 2025 |
| Primary completion | 30 September 2025 |
| Estimated completion | 30 October 2025 |
| Sites | 1 location across Brazil |
Drugs / interventions tested
- Automatic lateralization therapy
- Supine Positioning
Conditions studied
- Intensive Care Units — all drugs for Intensive Care Units →
Sponsor
University of Pernambuco
Who can join
18 and older, any sex, with Intensive Care Units. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
New devices have been used in intensive care to optimize respiratory function in critically ill patients, such as automatic lateralization therapy. However, the times and angles used vary widely, and there is no clear evidence of cardiovascular safety and immediate effects, which represents a gap in the literature. This quasi-experimental study aims to evaluate the imediact efficacy and cardiorespiratory safety of automatic lateralization therapy in critically ill patients under invasive mechanical ventilation. The primary outcomes include changes in ventilation distribution and end-expiratory impedance variation. Secondary outcomes include respiratory mechanics, vital signs, and adverse events.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT07087600
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Intensive Care Units
Currently open trials in the same condition.
- NCT06999863 — Oscillometric Blood Pressure Measurement: Evaluation of the Effect of Wearing a Sleeve and the Type of Measurement Algor · recruiting
- NCT07193069 — Clinical and Biological Signs of Dapagliflozin Overdose in ICU Patients With Metformin Poisoning · recruiting
- NCT07052123 — Non-Invasive Blood Pressure Monitoring in ICU Patients Using the DARE Device · NA · recruiting
- NCT07052604 — Antibiotic Treatment for Pneumonia Caused by Stenotrophomonas Maltophilia in ICU Patients · recruiting
- NCT05466708 — Safety and Efficacy of Esketamine Combined With Dexmedetomidine for Sedation of Mechanically Ventilated Patients · Phase 4 · recruiting
Other University of Pernambuco trials
Trials by the same sponsor.
- NCT07323472 — Body Lateralization and Its Effects on Respiratory Drive, Ventilation, and Pulmonary Aeration in Critically Ill Patients · NA · recruiting
- NCT07164586 — Early Detection of Acute Respiratory Failure Using an Intelligent Respiratory Monitoring System · active not recruiting
- NCT06296381 — Normative Values for Peripheral Muscle Strength in Critical Patients and Healthy Individuals · recruiting
- NCT06044896 — Physiology of Body Lateralization on Regional Lung Ventilation Study · NA · completed
- NCT05055440 — Evaluation of Peripheral Muscle With Ultrassonografic of Critical Patients With Covid-19 · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07087600 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Pernambuco
- Last refreshed: 25 November 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07087600.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing