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NCT07085949
Effect of Different Positive End-Expiratory Pressure (PEEP) Levels on Optic Nerve Sheath Diameter
trial testing 5 cmH2O PEEP in Optic Nerve Sheath Diameter in 105 participants. Completed in 2 January 2026.
1 January 2026
Quick facts
| Lead sponsor | Izmir City Hospital |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 105 |
| Start date | 30 July 2025 |
| Primary completion | 1 January 2026 |
| Estimated completion | 2 January 2026 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- 5 cmH2O PEEP
- 10 cmH2O PEEP
Conditions studied
- Optic Nerve Sheath Diameter — all drugs for Optic Nerve Sheath Diameter →
Sponsor
Izmir City Hospital
Who can join
Adults 18 to 65, any sex, with Optic Nerve Sheath Diameter. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this prospective observational study is to evaluate the effects of different PEEP values on the optic nerve sheath diameter (ONSD), a noninvasive indicator of intracranial pressure (ICP), in patients undergoing vertebral surgery. The main question it aims to answer is how mechanical ventilation setting of 5 and 10 cmH2O PEEP effect optic nerve sheath diameter after surgery at extubation.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT07085949
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Optic Nerve Sheath Diameter
Currently open trials in the same condition.
- NCT07525648 — Comparison of the Effects of Sevoflurane and Desflurane on Optic Nerve Sheath Diameter During Laparoscopic Surgery · NA · recruiting
- NCT06979999 — The Effects of Positive End-expiratory Pressure (PEEP) on Optic Nerve Sheath Diameter in Laparoscopic Cholecystectomy · NA · recruiting
Other Izmir City Hospital trials
Trials by the same sponsor.
- NCT07480252 — Tecar Therapy in Patients With Lumbar Radiculopathy · NA · not yet recruiting
- NCT07418463 — Effects of Repeated Electroconvulsive Therapy Sessions on Anesthetic Requirements · not yet recruiting
- NCT07420452 — Silac Versus Phenol for the Treatment of Pilonidal Sinus Disease: A Randomized Controlled Trial · NA · not yet recruiting
- NCT07378241 — Effects of Patients' Hormone Levels on Sedoanalgesia · not yet recruiting
- NCT07465510 — Ultrasound vs. Auscultation and Fiberoptic Bronchoscopy for Double-Lumen Tube Placement · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07085949 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Izmir City Hospital
- Last refreshed: 24 February 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07085949.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing