Last reviewed · How we verify
NCT07084740: EMoVaLP
Study and Modeling of Perforator Flap Vascularization
NA trial testing PeriCam and PeriFlux measurements in Reconstructive Surgery Using Pedicled Perforating or Free Perforating Flaps in 20 participants. Currently enrolling.
15 July 2026
Quick facts
| Lead sponsor | University Hospital, Montpellier |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | diagnostic |
| Enrollment | 20 |
| Start date | 15 February 2026 |
| Primary completion | 15 July 2026 |
| Estimated completion | 15 July 2026 |
| Sites | 1 location across France |
Drugs / interventions tested
- PeriCam and PeriFlux measurements
Conditions studied
- Reconstructive Surgery Using Pedicled Perforating or Free Perforating Flaps — all drugs for Reconstructive Surgery Using Pedicled Perforating or Free Perforating Flaps →
- Pelvic Eschar — all drugs for Pelvic Eschar →
- Traumatic Pathology of the Lower and/or Upper Limb — all drugs for Traumatic Pathology of the Lower and/or Upper Limb →
Sponsor
University Hospital, Montpellier
Who can join
Adults 18 to 70, any sex, with Reconstructive Surgery Using Pedicled Perforating or Free Perforating Flaps or Pelvic Eschar. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The aim of reconstructive surgery is to restore physical integrity altered by trauma, congenital malformations or cancerous pathologies. Several techniques are available, including flap surgery, which enables tissue to be moved from one anatomical location to another. Perforating skin/subcutaneous flaps are segments of skin and subcutaneous cellular tissue vascularized by a feeder vascular pedicle. This surgical technique has virtually zero donor-site morbidity, as it is no longer necessary to harvest muscle to ensure reliable vascularization of the flap. Flap vascularization is a variable mechanism, complex to describe and understand. For cutaneous and subcutaneous (fatty) flaps, which account for the majority of flaps used, perforator flaps (vascularized by a subcutaneous perforator artery) have become the benchmark. Unfortunately, their vascularization is currently poorly understood, and depends on experimental work carried out on fresh cadaveric anatomical specimens. These cadaveric studies fail to take into account several key factors influencing perforasomes (perforasome: skin territory vascularized by a pedicle), namely body temperature, blood pressure, heart rate, intraoperative patient position and biological parameters.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07084740
- Europe PMC full search
- ASCO Meeting Library
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- bioRxiv preprints
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07084740 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University Hospital, Montpellier
- Last refreshed: 13 April 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07084740.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing