Last reviewed · How we verify
NCT07084194
Impact of Integrating Two Nano Based Irrigants With Two Activation Techniques in Treatment of Teeth With Acute Pulpitis on Postoperative Pain and Flare up Incidence
NA trial testing Chitosan Nanoparticles Irrigant in Postoperative Pain in 64 participants. Not yet recruiting.
1 July 2026
Quick facts
| Lead sponsor | Minia University |
|---|---|
| Phase | NA |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | other |
| Enrollment | 64 |
| Start date | 10 September 2025 |
| Primary completion | 1 July 2026 |
| Estimated completion | 10 August 2026 |
Drugs / interventions tested
- Chitosan Nanoparticles Irrigant — full drug profile →
- aloe vera nanoparticles irrigant
- Diode Laser Activation
- ultrasonic activator
Conditions studied
- Postoperative Pain — all drugs for Postoperative Pain →
- Flare up — all drugs for Flare up →
- Flare Up, Symptom — all drugs for Flare Up, Symptom →
Sponsor
Minia University
Who can join
Eligibility, any sex, with Postoperative Pain or Flare up. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study aimed to evaluate and compare impact of integrating passive ultrasonic activation and laser activation with nano-chitosan and aloe vera in terms of postoperative pain and flare-up incidence in a randomized clinical trial.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07084194
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Chitosan Nanoparticles Irrigant
Trials testing the same drug.
- NCT06172023 — Evaluation of Antimicrobial Efficacy and Postoperative Pain After Using Silver Nanoparticles and Chitosan Nanoparticles · NA · completed
Other recruiting trials for Postoperative Pain
Currently open trials in the same condition.
- NCT07452120 — DIPB vs. SIFIB for Postoperative Analgesia After Hip Surgery · NA · recruiting
- NCT07396688 — Comparative Evaluation of the Effects of Calcium Hydroxide and BIO-C Temp Medicaments on Postoperative Pain in Patients · NA · recruiting
- NCT07413055 — Comparative Efficacy Of 4 mg VS. 8 mg Submucosal Dexamethasone In Postoperative Pain Management After Dental Implant Sur · Phase 3 · recruiting
- NCT07496086 — External Oblique Intercostal Block Versus Transversus Abdominis Plane Combined With Rectus Sheath Block on Postoperative · NA · recruiting
- NCT07396545 — External Oblique Intercostal Block Versus Erector Spinae Plane Block on Postoperative Pain in Laparoscopic Radical Gastr · NA · recruiting
Other Minia University trials
Trials by the same sponsor.
- NCT07525687 — Temporary Uterine Tourniquet Application Versus Local Myometrial Epinephrine Injection During Laparoscopic Myomectomy · NA · not yet recruiting
- NCT07525674 — Vacuum Sealing Drainage (VSD) in Promoting Wound Healing and Reducing Complications in Post-Infected Obstetric and Gynec · NA · not yet recruiting
- NCT07529587 — Laparoscopic Umbilico-uterine Trunk Clipping Approach in the Management of Enhanced Myometrial Vascularity · NA · not yet recruiting
- NCT07500558 — Ultrasound Guided Infratemporal Sphenopalatine Ganglion Supravoltage Versus Standard Voltage Pulsed Radiofrequency for P · NA · not yet recruiting
- NCT07428057 — Postoperative Hypocalcemia After Thyroidectomy · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07084194 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Minia University
- Last refreshed: 24 July 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07084194.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing