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NCT07081607

Golidocitinib With Azacitidine and Chidamide in Patients With Peripheral T-cell Lymphoma.

Not yet recruiting Phase 2 Last updated 23 July 2025
What this trial tests

Phase 2 trial testing golidocitinib with azacytidine and chidamide in Peripheral T-Cell Lymphoma, Not Classified in 30 participants. Not yet recruiting.

Timeline
15 July 2025
Primary endpoint
16 July 2026
16 July 2028

Quick facts

Lead sponsorRuijin Hospital
PhasePhase 2
StatusNot yet recruiting
Study typeINTERVENTIONAL
Allocationna
Designsingle group
Maskingnone
Primary purposetreatment
Enrollment30
Start date15 July 2025
Primary completion16 July 2026
Estimated completion16 July 2028

Drugs / interventions tested

Conditions studied

Sponsor

Ruijin Hospital

Who can join

18 and older, any sex, with Peripheral T-Cell Lymphoma, Not Classified. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

In decades, the outcome of patients with peripherial T-cell lymphomas is dismal, especially in relapsed or refractory population. After failure to the frontline treatment, patients have limited treatment options and elderly population usually have no chance to undergo transplantation due to age or comorbidity, etc. Golidocitinib and chidamide were approved in treating r/r PTCL in China, while azacytidine has been demonstrated its anti-tumor activity in PTCL as well. This study aims to explore the efficacy and safety of golidocitinib combined with azacytidine and chidamide in the patients with peripheral T-cell lymphoma who are eligible for intensive chemotherapy or transplantation.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. JAK Inhibitors in the Treatment of T-Cell Lymphomas: Current Evidence and Future Directions
    · 2026

Verify or expand the search:

Other recruiting trials for Peripheral T-Cell Lymphoma, Not Classified

Currently open trials in the same condition.

Other Ruijin Hospital trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07081607.

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