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NCT07081399: CP
the Effect of Adult Intubated Patient Clinical Pathway on Post-extubation Complications Prevention
EARLY_PHASE1 trial testing ETT cuff pressure monitoring, ETT suctioning, cough augmentation technique, swallowing exercises,: Nebulized budesonide 1mg and IV methylprednisolone 40 mg we in Dysphagia in 80 participants. Currently enrolling.
8 March 2025
Quick facts
| Lead sponsor | Damanhour University |
|---|---|
| Phase | EARLY_PHASE1 |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | supportive care |
| Enrollment | 80 |
| Start date | 8 August 2024 |
| Primary completion | 8 March 2025 |
| Estimated completion | 1 August 2025 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- ETT cuff pressure monitoring, ETT suctioning, cough augmentation technique, swallowing exercises,: Nebulized budesonide 1mg and IV methylprednisolone 40 mg we
Conditions studied
- Dysphagia — all drugs for Dysphagia →
- Dysphagia Rehabilitation — all drugs for Dysphagia Rehabilitation →
Sponsor
Damanhour University
Who can join
Adults 18 to 60, any sex, with Dysphagia or Dysphagia Rehabilitation. Patients with the condition only — healthy volunteers not accepted.
What's being measured
Primary outcomes are the specific endpoints the trial is designed to prove or disprove.
-
prevention of laryngeal edema
Time frame: 72 hours after extubation
measured by respiratory distress observation score that it ranges from 0-16. the high score indicates sever respiratory distress -
laryngospasm
Time frame: 72 hours after extubation
measured by four point scale. it composed from 4 grades, grade 0 indicates no laryngospasm, grade 3 indicates severe degree of laryngospasm. -
dysphagia
Time frame: 72 hours after extubation
measured by Gugging Swallowing Screen scale that it ranges from 0 -20. the high score indicates severe dysphagia
Sponsor's own description
Post- extubation complications delay the complete recovery of critically ill patient. The clinical pathway is one strategies that help to manage and control these complications.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07081399
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Dysphagia
Currently open trials in the same condition.
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Other Damanhour University trials
Trials by the same sponsor.
- NCT07307911 — Coenzyme Q10 for Neuroprotection in Paclitaxel-Induced Neuropathy · Phase 2 · completed
- NCT07341893 — Sacubitril-valsartan in Patients With Heart Failure. · NA · recruiting
- NCT07063628 — Triglyceride-Glucose Indices and Left Ventricular Speckle Tracking in Predicting Coronary Artery Disease Severity · completed
- NCT06849388 — Effect of HeartMath Intervention on Stress, Emotional Vitality and Sense of Coherence · NA · recruiting
- NCT07179302 — Pre- and Post-TAVI Patient Assessment: Advancing Outcome Precision in Aortic Valve Therapy · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07081399 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Damanhour University
- Last refreshed: 22 July 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07081399.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing