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NCT07078474
Comparison of Skin Condition After Hyaluronic Acid Application on Dry vs. Moist Skin
NA trial testing Topical Hyaluronic Acid in Skin Hydration in 23 participants. Completed in 9 July 2025.
9 July 2025
Quick facts
| Lead sponsor | University of Split, School of Medicine |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 23 |
| Start date | 18 June 2025 |
| Primary completion | 9 July 2025 |
| Estimated completion | 9 July 2025 |
| Sites | 1 location across Croatia |
Drugs / interventions tested
- Topical Hyaluronic Acid
Conditions studied
- Skin Hydration — all drugs for Skin Hydration →
- Hyaluronic Acid — all drugs for Hyaluronic Acid →
Sponsor
University of Split, School of Medicine
Who can join
Adults 18 to 50, any sex, with Skin Hydration or Hyaluronic Acid. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study aims to compare the effects of two different methods of applying hyaluronic acid (HA) on skin parameters in healthy individuals. HA is a widely used ingredient in skincare products due to its hydrating properties. However, it is unclear whether applying HA to dry or pre-moistened skin provides better results in terms of skin hydration and texture. In this non-invasive, interventional trial, 23 healthy volunteers aged 18 to 50 will be randomly assigned to two groups. One group will apply HA to dry skin, while the other will apply HA to moistened skin. Skin parameters will be measured before and after the intervention to assess hydration, transepidermal water loss, and overall skin condition. The aim is to determine the optimal method of HA application that maximizes its effectiveness in improving skin quality. Participants may benefit from improved skin hydration and increased awareness of the best application method for their skin type. No significant risks are expected from participation.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT07078474
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Skin Hydration
Currently open trials in the same condition.
- NCT07493850 — Study to Assess the Efficacy of EMC-CAP-2025A on Age-Related Skin Parameters in Healthy Individuals · Phase 2 · active not recruiting
Other University of Split, School of Medicine trials
Trials by the same sponsor.
- NCT07286487 — Glycyrrhetinic Acid and Acute Irritant Dermatitis · NA · not yet recruiting
- NCT07314944 — Maternal Sleep and Lifestyle, Metabolic Health, and Perinatal Outcomes in Gestational Diabetes · recruiting
- NCT07140107 — Effectiveness of Original vs. AI-Generated Plain Language Summaries of Systematic Reviews · NA · enrolling by invitation
- NCT07079371 — Micellar Water and the Skin Barrier: Comparing Rinsing vs. Non-Rinsing Application · NA · active not recruiting
- NCT07017127 — Remission of Type 2 Diabetes With Lifestyle Intervention · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07078474 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Split, School of Medicine
- Last refreshed: 22 July 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07078474.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing