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NCT07073391: LamCircuits
Clinical Study of How Information Flows Across the Human Cortical Sheet Layers (Laminae), Aiming to Discover Key Principles of Laminar Circuits and Information Flow for Complex Behavior.
trial testing Recording with laminar arrays in Neuronal Mechanisms in 100 participants. Not yet recruiting.
1 September 2030
Quick facts
| Lead sponsor | Christopher I. Petkov |
|---|---|
| Status | Not yet recruiting |
| Study type | OBSERVATIONAL |
| Enrollment | 100 |
| Start date | 1 September 2026 |
| Primary completion | 1 September 2030 |
| Estimated completion | 1 September 2032 |
Drugs / interventions tested
- Recording with laminar arrays
Conditions studied
- Neuronal Mechanisms — all drugs for Neuronal Mechanisms →
- Laminar Circuits — all drugs for Laminar Circuits →
Sponsor
Christopher I. Petkov
Who can join
Adults 18 to 80, any sex, with Neuronal Mechanisms or Laminar Circuits. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This is a basic science study of a missing dimension of human brain function, how information flows the six layers of the brain. The research will involve neurosurgery patients and controls in laminar-resolution functional MRI at 7 Tesla during a working memory and language task. The neurosurgery patients will be involved in intracranial recordings with FDA approved electrodes capable of recording across the cortical layers, or electrodes with FDA Investigational Device Exemption. The neurosurgery patients will also be able to provide tissue samples for genomics research from tissue that would be clinically removed, resected or disrupted as part of the clinical treatment. The outcome is unprecedented insights into this missing dimension of human brain function which will help to advance biomedical science and could be crucial for developing better patient diagnostic and treatment options for a host of brain disorders where laminar information flow is disrupted but currently cannot be effectively studied.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
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Related trials
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07073391 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Christopher I. Petkov
- Last refreshed: 17 December 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07073391.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing