NCT07070843

Effects of Two Different Eye Care Practices on Eye Complications in Mechanically Ventilated Intensive Care Patients

Recruiting now NA Last updated 27 January 2026

What this trial tests

NA trial testing Control Group: Standard Eye Care Group in Eye Care in 156 participants. Currently enrolling.

Timeline

1 July 2025

Primary endpoint
1 May 2026

1 October 2026

Quick facts

Lead sponsor	Istanbul Saglik Bilimleri University
Phase	NA
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	other
Enrollment	156
Start date	1 July 2025
Primary completion	1 May 2026
Estimated completion	1 October 2026
Sites	1 location across Turkey (Türkiye)

Drugs / interventions tested

• Control Group: Standard Eye Care Group
• Intervention Group 1: Eye Care Using an Eye Care Kit
• Intervention Group 2: Eye Care According to an Eye Care Protocol
• Intervention Group 3: Eye Care Using Both the Eye Care Protocol and the Eye Care Kit

Conditions studied

• Eye Care — all drugs for Eye Care →
• Nursing Care — all drugs for Nursing Care →
• Intensive Care Unit — all drugs for Intensive Care Unit →

Sponsor

Istanbul Saglik Bilimleri University

Who can join

18 Days and older, any sex, with Eye Care or Nursing Care. Patients with the condition only — healthy volunteers not accepted.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

• Conjunctival Edema in Critically Ill Patients
  Time frame: Data collection was conducted for 10 consecutive days, beginning 24 hours after admission to the intensive care unit.
  Conjunctival Edema (Chemosis): Chemosis is the edema of the conjunctiva, which is a thin, transparent membrane covering the inner surface of the eyelids and the white part of the eyes (sclera). It refers to the swelling of this membrane that lines the ocular surface.
• Ocular Infections in Critically Ill Patients
  Time frame: Data collection was conducted for 10 consecutive days, beginning 24 hours after admission to the intensive care unit.
  Signs and Symptoms of Ocular Infection: Redness, ocular discharge, crusting along the eyelid margins, adhesion of eyelashes (eyelashes sticking together), corneal discoloration (loss of corneal transparency), periorbital edema.
• Dry Eye in Critically Ill Patients
  Time frame: Data collection was conducted for 10 consecutive days, beginning 24 hours after admission to the intensive care unit.
  Dry Eye: Dry eye is a multifactorial disease of the ocular surface, defined by tear film instability and associated with symptoms including ocular discomfort, burning sensation, irritation, dryness, visual blurring, and foreign body sensation."

Sponsor's own description

This study was designed as a prospective, randomized controlled experimental study aiming to compare different approaches to eye care in intensive care patients receiving mechanical ventilation. In this study, patients receiving mechanical ventilation in the intensive care unit will be randomly assigned to four groups using a simple randomization method:

1. Control Group: Standard Eye Care
2. Intervention Group 1: Eye Care with Eye Care Kit
3. Intervention Group 2: Eye Care According to Eye Care Protocol
4. Intervention Group 3: Eye Care with Both Protocol and Eye Care Kit Research Hypotheses H1: Eye care provided using a care protocol is more effective in preventing the development of complications compared to standard eye care.

H2: Eye care provided using an eye care kit is more effective in preventing the development of ocular complications compared to standard eye care.

H3: The combined use of an eye care kit and a care protocol is more effective in preventing the development of ocular complications compared to using the care protocol alone.

H4: The use of an eye care kit is more effective in preventing the development of ocular complications compared to the use of a care protocol.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.