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NCT07069231
Effect of Bio-activation on Epithelial and Connective Cell Adhesion to Titanium Abutments: Split Mouth Clinical Trial
NA trial testing the test group were placed in an Argon plasma reactor in Missing Tooth/Teeth in 20 participants. Not yet recruiting.
30 October 2025
Quick facts
| Lead sponsor | Universita degli Studi di Genova |
|---|---|
| Phase | NA |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 20 |
| Start date | 15 July 2025 |
| Primary completion | 30 October 2025 |
| Estimated completion | 30 October 2025 |
Drugs / interventions tested
- the test group were placed in an Argon plasma reactor
Conditions studied
- Missing Tooth/Teeth — all drugs for Missing Tooth/Teeth →
Sponsor
Universita degli Studi di Genova — full company profile →
Who can join
Eligibility, any sex, with Missing Tooth/Teeth. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The aim of this "in vivo" controlled trial is to assess soft tissue cell adhesion to titanium abutments subjected to different cleaning procedures - no treatment (as they come from the industry), and cleaning by plasma- at an early healing time. In fact, the primary aim is Quantity and Quality of soft tissue adhesion at the microscopic level (e.g Fibronectin, Integrin-actin). The secondary Aim - Clinical parameters and outcomes - BOP, PPD, MBL (Marginal Bone Level to check influence of plasmapp-treated abutments). The null hypothesis of the study was that the cleaning procedure applied to implant abutments has no effect on soft tissue cell adhesion and MBL at an early healing time.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07069231
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of the test group were placed in an Argon plasma reactor
Trials testing the same drug.
- NCT07082088 — Abutment Hydrophilicity on Soft Tissue Morphogenesis · NA · not yet recruiting
Other Universita degli Studi di Genova trials
Trials by the same sponsor.
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- NCT07094269 — Protocol of the Packer Managing Fatigue Program Versus Standard Information to Improve Energy Conservation Self-Efficacy · NA · recruiting
- NCT06378502 — The Effect of Different Antibiotic Protocols on Peri-implant Tissue Health · Phase 4 · not yet recruiting
- NCT06573918 — EMG-Assessed Paratonia: A New Approach to Response Inhibition · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07069231 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Universita degli Studi di Genova
- Last refreshed: 16 July 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07069231.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing