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NCT07065253
CHOICE KERGUELEN 1: Consequences of Longterm Confinement on Immunity in the Sub-Antarctic Islands: Inclusion of Volunteers Before Departure to the Kerguelen Islands
trial testing blood ponction in Human Health in Extreme Conditions in 9 participants. Completed in 25 September 2025.
25 September 2025
Quick facts
| Lead sponsor | University Hospital, Angers |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 9 |
| Start date | 25 September 2025 |
| Primary completion | 25 September 2025 |
| Estimated completion | 25 September 2025 |
| Sites | 1 location across France |
Drugs / interventions tested
- blood ponction
- urines collection
- hair collection
- saliva collection — full drug profile →
- stools collection
Conditions studied
- Human Health in Extreme Conditions — all drugs for Human Health in Extreme Conditions →
Sponsor
University Hospital, Angers
Who can join
18 and older, any sex, with Human Health in Extreme Conditions. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Living for long periods in extreme environments-like Antarctic research stations or space missions-can have a significant impact on human health, especially on the immune system. Scientists have observed that people in such isolated conditions often experience more infections and a reactivation of viruses that usually stay dormant in the body, such as Herpes viruses. These changes affect both parts of the immune system: the rapid-response "innate" system and the slower, more specific "adaptive" system. These immune disruptions may be caused by multiple stressors: ongoing psychological stress, disturbed sleep and light cycles (circadian rhythm disruption), and the challenges of living in confined, isolated, and extreme environments. While space missions and Antarctic overwintering programs have provided some insight into these issues, scientists still lack a detailed understanding of how the immune system adapts-or fails to adapt-over time in such conditions. To help fill this gap, the CHOICE Kerguelen 1 study will recrut a group of healthy young adults who will spend one year (from November 2025 to November 2026) in Port-aux-Français, a remote French research station on the Kerguelen Islands in the sub-Antarctic. These volunteers are participating in a civic service program and will be living in a highly isolated environment for the duration of their mission. The CHOICE Kerguelen 1 study is conducted in collaboration with the French Polar Institute (IPEV).The goal of the study is to collect and store a broad range of biological samples-including blood, saliva, stool, urine, and hair-from these volunteers before they leave for the island, to have baseline medical state and baseline biological samples. These samples will integrate in to healthy volunteer biobank of CHU Angers, a type of biological archive that provided control samples for CHOICE Kerguelen 2 - a clinical study relating to follow-up of volunteers during civic service on the Kerguelen Islands
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT07065253
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of blood ponction
Trials testing the same drug.
- NCT07275489 — CHOICE KERGUELEN 2 : Consequences of Longterm Confinement on Immunity in the Sub-Antarctic Islands : Follow-up of Volunt · recruiting
Other recruiting trials for Human Health in Extreme Conditions
Currently open trials in the same condition.
- NCT07275489 — CHOICE KERGUELEN 2 : Consequences of Longterm Confinement on Immunity in the Sub-Antarctic Islands : Follow-up of Volunt · recruiting
Other University Hospital, Angers trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07065253 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University Hospital, Angers
- Last refreshed: 5 December 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07065253.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing