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NCT07065214: OVAPLAS
Argon Plasma Treatment for Ovarian Endometrioma Compared to Standard Cystectomy
NA trial testing APC in Endometriosis in 72 participants. Currently enrolling.
1 March 2027
Quick facts
| Lead sponsor | Erbe Elektromedizin GmbH |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 72 |
| Start date | 26 November 2025 |
| Primary completion | 1 March 2027 |
| Estimated completion | 30 September 2027 |
| Sites | 1 location across Germany |
Drugs / interventions tested
- APC
- Lap bipolar forceps
Conditions studied
- Endometriosis — all drugs for Endometriosis →
Sponsor
Erbe Elektromedizin GmbH — full company profile →
Who can join
Adults 18 to 40, female only, with Endometriosis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The study is a prospective, monocentric, randomized controlled, two-armed, pilot-study conducted at Department for Women's Health, Tuebingen, Germany. In this Post Market Study it will be determined whether and to what extent the two surgical procedures for ovarian endometrioma treatment (standard cystectomy versus APC) may affect the ovarian reserve by comparing changes in serum AMH levels after treatment. Seventy-two (72) patients who meet all eligibility criteria will undergo surgical procedure. The patients will be randomized into the group with standard cystectomy treatment or with APC treatment. Per group n=36 patients will be treated i.e., 1:1 randomization. A pre-specified primary endpoint analysis is planned after the last patient has undergo Visit 4 (Follow-up after 6 months) to analyze the primary endpoint. Screening takes place during the first visit (V1). During the second visit (V2) the participants will receive the ovarian endometriosis treatment procedure either with the APC or the standard cystectomy. Standard procedure (standard cystectomy) will be performed for additional endometriosis lesions. The follow up visits (V3 - V5) will take place after three, six and twelve months. Visit 3 and Visit 4 will take place at the study site and AMH will be measured. Whereas Visit 5 will take place via telemedical contact, i.e. phone call.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07065214
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Erbe Elektromedizin GmbH trials
Trials by the same sponsor.
- NCT06249841 — Feasibility of Cryobiopsy from the Bile Duct - CRYLEO · NA · completed
- NCT06020573 — Evaluation of Safety and Performance of Intraoperative Detection of Light Signals During Electrosurgical Breast Cancer R · NA · completed
- NCT05587491 — HybridAPC for Gastric Mucosal Ablation in Obese Patients. · NA · completed
- NCT03621319 — Eradicating Barrett's Esophagus Using Radiofrequency Ablation or a Novel Hybrid Argon Plasma Coagulation Technique · NA · terminated
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07065214 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Erbe Elektromedizin GmbH
- Last refreshed: 28 November 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07065214.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing