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NCT07061990

The Role of Inflammatory Markers in OSAHS-Related White Matter Lesions and Asymptomatic Lacunar Infarction

Completed Last updated 14 July 2025
What this trial tests

trial testing Polysomnography (PSG) in Obstructive Sleep Apnea-hypopnea Syndrome in 119 participants. Completed in 1 May 2023.

Timeline
1 May 2022
Primary endpoint
1 May 2023
1 May 2023

Quick facts

Lead sponsorYanpeng Li
StatusCompleted
Study typeOBSERVATIONAL
Enrollment119
Start date1 May 2022
Primary completion1 May 2023
Estimated completion1 May 2023
Sites1 location across China

Drugs / interventions tested

Conditions studied

Sponsor

Yanpeng Li

Who can join

18 and older, any sex, with Obstructive Sleep Apnea-hypopnea Syndrome. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This retrospective observational study aims to investigate the potential role of inflammatory markers associated with Obstructive Sleep Apnoea-Hypopnoea Syndrome (OSAHS) in the pathogenesis of white matter lesions (WML) and asymptomatic lacunar infarction (ALI). The study compares inflammatory marker levels (SAA, TNF-α, IL-6) and the severity of white matter lesions among patients with OSAHS alone, OSAHS with ALI, and a healthy control group to explore the relationship between the severity of OSAHS, inflammation, and cerebrovascular changes.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

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