NCT07059195

Non-Invasive Techniques to Maintain Neck Flexion and Reduce Anastomotic Tension After Tracheal Resection

Recruiting now NA Last updated 10 July 2025

What this trial tests

NA trial testing cervical collar or cervical-thoracic orthosis. in Maintain Neck Flexion and Reduce Anastomotic Tension After Tracheal Resection in 30 participants. Currently enrolling.

Timeline

30 June 2025

Primary endpoint
30 June 2027

30 June 2027

Quick facts

Lead sponsor	Sohag University
Phase	NA
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	30
Start date	30 June 2025
Primary completion	30 June 2027
Estimated completion	30 June 2027
Sites	1 location across Egypt

Drugs / interventions tested

• cervical collar or cervical-thoracic orthosis.
• chin-to-chest (Grillo) suturing

Conditions studied

• Maintain Neck Flexion and Reduce Anastomotic Tension After Tracheal Resection — all drugs for Maintain Neck Flexion and Reduce Anastomotic Tension After Tracheal Resection →

Sponsor

Sohag University

Who can join

Adults 6 Months to 80, any sex, with Maintain Neck Flexion and Reduce Anastomotic Tension After Tracheal Resection. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Tracheal surgery represents a relatively recent advancement in the field of thoracic surgery. The trachea has unique anatomical and physiological challenges that historically rendered surgical manipulation both risky and limited. Early interventions involving the trachea were primarily restricted to emergency tracheostomy procedures, typically performed as life-saving measures during acute airway obstruction (1). Attempts at tracheal reconstruction were largely unsuccessful due to the absence of suitable anesthesia, inadequate surgical tools, and the prevailing belief that tracheal cartilage lacked sufficient regenerative. As a result, tracheal resection and reconstruction were long considered unfeasible (2).

The modern era of tracheal surgery began to take shape in the mid-20th century. While early attempts at tracheal resection were performed with limited success, it was the pioneering work of Dr. Hermes C. Grillo in the 1960s that truly transformed the field. Through systematic study of tracheal anatomy, vascular supply, and biomechanics, Dr. Grillo developed standardized and safe techniques for segmental tracheal resection followed by primary end-to-end anastomosis. His work demonstrated that segmental resection of the trachea followed by primary end-to-end anastomosis was feasible and safe (3)(4).

Publications & conference data

No peer-reviewed publications indexed yet for this trial.