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NCT07058129
Deep Cervical Lymphatic Venous Anastomosis in the Treatment of Alzheimer's Disease (CLEAN-AD Registry)
trial testing Deep cervical lymphatic venous anastomosis in Alzheimers Disease in 814 participants. Not yet recruiting.
30 July 2028
Quick facts
| Lead sponsor | Beijing Tiantan Hospital |
|---|---|
| Status | Not yet recruiting |
| Study type | OBSERVATIONAL |
| Enrollment | 814 |
| Start date | 30 July 2025 |
| Primary completion | 30 July 2028 |
| Estimated completion | 30 July 2029 |
| Sites | 1 location across China |
Drugs / interventions tested
- Deep cervical lymphatic venous anastomosis
Conditions studied
- Alzheimers Disease — all drugs for Alzheimers Disease →
Sponsor
Beijing Tiantan Hospital
Who can join
18 and older, any sex, with Alzheimers Disease. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This multicenter, prospective registry is to evaluate the efficacy and safety of deep cervical lymphatic venous anastomosis (DC-LVA) in reduing the clinical dementia rating-sum of boxes (CDR-SB) score of Alzheimer's Disease (AD) patients at 12 months after surgery in the real-world.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Deep cervical lymphaticovenous anastomosis for Alzheimer's disease: A narrative review.
Chen Q, Wen Q, Zhong T, Liu J, et al · · 2025 · cited 2× · PMID 41457949 · DOI 10.1002/alz.71038
Verify or expand the search:
- PubMed search for NCT07058129
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Alzheimers Disease
Currently open trials in the same condition.
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- NCT07169578 — A Study of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease · Phase 3 · recruiting
- NCT06484244 — Locomotion Adaptation Deficits in Older Adults With Mild Cognitive Impairment and Alzheimers Disease · NA · recruiting
- NCT07177352 — Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies · Phase 3 · recruiting
- NCT05552157 — A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by · Phase 2, PHASE3 · recruiting
Other Beijing Tiantan Hospital trials
Trials by the same sponsor.
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- NCT07520370 — Effect of Perioperative Ulinastatin on Postoperative Stroke in Patients With Brain Tumor · NA · not yet recruiting
- NCT07526987 — Efficacy and Safety of Minocycline in Patients With Acute Ischaemic Stroke Receiving Intravenous Thrombolysis · Phase 3 · not yet recruiting
- NCT07591207 — The Efficacy and Safety of Loxoprofen Sodium Patch in Relieving Postoperative Pain After Laparoscopic Surgery · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07058129 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Beijing Tiantan Hospital
- Last refreshed: 10 July 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07058129.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing