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NCT07057258
Injection Versus Suture Repair of Laryngeal Clefts
NA trial testing Endoscopic suture repair in Laryngeal Cleft in 128 participants. Enrolling by invitation.
1 September 2026
Quick facts
| Lead sponsor | Oregon Health and Science University |
|---|---|
| Phase | NA |
| Status | ENROLLING BY INVITATION |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | treatment |
| Enrollment | 128 |
| Start date | 1 September 2025 |
| Primary completion | 1 September 2026 |
| Estimated completion | 30 December 2026 |
| Sites | 2 locations across United States |
Drugs / interventions tested
- Endoscopic suture repair
- Injection laryngoplasty
Conditions studied
- Laryngeal Cleft — all drugs for Laryngeal Cleft →
- Dysphagia — all drugs for Dysphagia →
Sponsor
Oregon Health and Science University
Who can join
Adults 12 Months to 10, any sex, with Laryngeal Cleft or Dysphagia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of the study is to learn more about a procedure that may be helpful for the participant's swallowing issues. The investigators are hoping to find out if one type of procedure is the same or better than another type of procedure at improving participant's issues with swallowing. Participants will get one of two procedures. One is called injection laryngoplasty (IL) and injects a gel into the back wall of the participant's airway to prevent food and liquid from falling in. The other procedure is called endoscopic suture repair (ER) and uses sutures to sew together and build up the back wall of the participant's airway to prevent food and liquid from falling in. Participants will be asked to have a number of tests and procedures. These include a modified barium swallow study, in which the participant drinks and eats foods and liquids with barium in them and X-rays are used to assess how the food moves through the participant's body. This will be done before the procedure and 3 months after the procedure. The investigators will also give participants questionnaires to complete before and after the procedure.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07057258
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07057258 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Oregon Health and Science University
- Last refreshed: 29 September 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07057258.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing