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NCT07056465
Exploring Adherence and Acceptability of an Intermittent Carbohydrate Restriction Regime in Free-Living Adults: A Feasibility Study
NA trial testing Intermittent Carbohydrate Restriction (ICR) Protocol in Healthy in 37 participants. Completed in 20 April 2024.
20 March 2024
Quick facts
| Lead sponsor | University of Surrey |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | prevention |
| Enrollment | 37 |
| Start date | 13 January 2023 |
| Primary completion | 20 March 2024 |
| Estimated completion | 20 April 2024 |
| Sites | 1 location across United Kingdom |
Drugs / interventions tested
- Intermittent Carbohydrate Restriction (ICR) Protocol
Conditions studied
- Healthy — all drugs for Healthy →
Sponsor
University of Surrey
Who can join
Adults 18 to 60, any sex, with Healthy. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study investigates a novel dietary approach called Intermittent Carbohydrate Restriction (ICR), which involves reducing carbohydrate intake on selected days of the week while allowing habitual eating on other days. Previous research suggests that intermittent dietary strategies may improve metabolic health and support better adherence compared to continuous calorie restriction. In this single-arm feasibility study, 40 healthy adults will follow the ICR protocol for 4 weeks. Outcomes including body weight, body fat percentage, waist circumference, and resting metabolic rate will be measured before and after the intervention. Dietary adherence, changes in habitual intake, and participant experiences will be assessed through food diaries, 24-hour recalls, questionnaires, and exit interviews. The primary aim is to evaluate the acceptability and adherence to the ICR protocol in free-living conditions. Secondary aims include exploring its effects on body composition and diet-related behaviours, with the goal of informing future long-term dietary interventions.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Exploring Adherence and Acceptability of an Intermittent Carbohydrate Restriction Regime (ICARB) in Free-Living Adults: A Feasibility Study.
Biyikoglu H, Tse YT, Ding R, Mold FE, et al · · 2026 · PMID 41536043 · DOI 10.1111/jhn.70188
Verify or expand the search:
- PubMed search for NCT07056465
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07056465 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Surrey
- Last refreshed: 9 July 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07056465.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing