Last reviewed · How we verify
NCT07052747
Periodontal Effects of Orthodontic Mini-Screws
trial testing Clinical periodontal assessment in Dental Implantation in 132 participants. Completed in 29 April 2025.
25 April 2025
Quick facts
| Lead sponsor | Dr. Mehmet Selim Yildiz |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 132 |
| Start date | 4 October 2024 |
| Primary completion | 25 April 2025 |
| Estimated completion | 29 April 2025 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Clinical periodontal assessment
Conditions studied
- Dental Implantation — all drugs for Dental Implantation →
- Peri-implant Mucositis — all drugs for Peri-implant Mucositis →
- Orthodontic Anchorage Procedures — all drugs for Orthodontic Anchorage Procedures →
- Gingival Inflammation and Bleeding — all drugs for Gingival Inflammation and Bleeding →
Sponsor
Dr. Mehmet Selim Yildiz
Who can join
Eligibility, any sex, with Dental Implantation or Peri-implant Mucositis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Orthodontic mini-screws (TADs) are commonly used to provide temporary anchorage and prevent unwanted tooth movement during orthodontic treatment. Their clinical success largely depends on their ability to remain stable under functional orthodontic loads. Stability is assessed in two phases: primary stability, which reflects immediate mechanical retention in bone, and secondary stability, which results from biological remodeling and healing over time. Multiple factors such as age, gender, bone characteristics, screw dimensions, and force magnitude may influence screw stability. Recent studies suggest that local inflammation around mini-screws, similar to peri-implantitis in dental implants, can compromise bone integrity and lead to screw failure. Inadequate oral hygiene and the absence of keratinized tissue at the insertion site are among the key risk factors associated with inflammation and soft tissue complications. Unlike traditional implants, mini-screws are often inserted at variable intraoral locations and subject to angular force vectors, which may further impact surrounding periodontal tissues. This cross-sectional clinical study aims to evaluate the effects of orthodontic mini-screw placement on general oral health and periodontal tissue status. The study will investigate site-specific and full-mouth periodontal parameters and explore potential associations between mini-screw stability, soft tissue characteristics, and signs of mucosal inflammation.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Periodontal health and orthodontic mini-screws: a cross-sectional study.
Yildiz MS, Ulutas PA, Akcalı A. · · 2026 · PMID 41968715 · DOI 10.5051/jpis.2503060153
Verify or expand the search:
- PubMed search for NCT07052747
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Dental Implantation
Currently open trials in the same condition.
- NCT06786221 — Accuracy, Stability and Safety of Orthodontic Mini-implant Template in the Infrazygomatic Crest Zone · NA · active not recruiting
- NCT06449391 — The Application of Root Analogy Implant in Immediate Implantation · NA · recruiting
- NCT05741749 — Immediate Implant Placement in the Posterior Region Combining Sealing Socket Abutment and Peri-implant Socket Filling. · NA · recruiting
- NCT05758337 — Vibropneumostimulation in the Rehabilitation After Dental Implantation · NA · recruiting
Other Dr. Mehmet Selim Yildiz trials
Trials by the same sponsor.
- NCT06491849 — Evaluation of Peri-implant Conditions of Orthodontic Mini Implants · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07052747 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Dr. Mehmet Selim Yildiz
- Last refreshed: 7 July 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07052747.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing