Last reviewed · How we verify
NCT07052526
Comparative Evaluation of Hydrophilic and Hydrophobic Sealants in Partially Erupted First Molars
NA trial testing Prevention in Dental Caries in 150 participants. Not yet recruiting.
1 January 2027
Quick facts
| Lead sponsor | Mansoura University |
|---|---|
| Phase | NA |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | prevention |
| Enrollment | 150 |
| Start date | 1 July 2025 |
| Primary completion | 1 January 2027 |
| Estimated completion | 1 April 2027 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Prevention
- Prevention of caries
- Prevention therapy — full drug profile →
Conditions studied
- Dental Caries — all drugs for Dental Caries →
Sponsor
Mansoura University
Who can join
Adults 5 to 7, any sex, with Dental Caries. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This randomized controlled clinical trial aims to evaluate and compare the retention, caries prevention, microleakage, and fluoride release of three types of pit and fissure sealants-hydrophilic, nanofilled hydrophobic, and conventional hydrophobic-applied to partially erupted first permanent molars in children aged 5 to 7 years. The study uses a split-mouth design and includes both clinical and laboratory evaluations over an 18-month period. Outcomes will assess sealant effectiveness with and without the use of a bonding agent.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07052526
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Prevention
Trials testing the same drug.
- NCT06262464 — An OCD Prevention Programme for at Risk Adults · NA · recruiting
- NCT05771233 — Effectiveness of Abdominal Muscle Strengthening and Pelvic Control in the Prevention of Dance Injuries · NA · unknown
- NCT03474575 — Early Supported Discharge and Enhanced Homecare After Emergency Department Admission for Acute Exacerbation of COPD · NA · completed
Other recruiting trials for Dental Caries
Currently open trials in the same condition.
- NCT06787261 — Involvement of Archaea in Carious Disease · NA · recruiting
- NCT06753669 — Mothers' Action Project for Child Health · NA · recruiting
- NCT07431463 — Effects of Different Remineralization Agents on the Progression of Non-Cavitated Approximal Carious Lesions in Primary T · NA · active not recruiting
- NCT07134114 — Occlusal Impact of Hall Crowns in Primary Molars · NA · recruiting
- NCT07181967 — SDF vs Fluoride Varnish for Streptococcus Mutans Reduction in Children · NA · recruiting
Other Mansoura University trials
Trials by the same sponsor.
- NCT05785377 — Neostigmine as an Adjuvant in Tranversus Abdominis Plane (TAP) Block in Cesarean Section Under Spinal Anesthesia · NA · not yet recruiting
- NCT07509567 — Conventional Palatal Crib Versus Bonded Spurs for Anterior Open Bite Treatment · NA · not yet recruiting
- NCT07393178 — Efficacy & Safety of High Power vs. Low Power Holmium Laser in Mini-PCNL for Large Renal Stones · NA · not yet recruiting
- NCT07436182 — Mitochondrial Redox Modulation in Newly Diagnosed Type 2 Diabetes: A Randomized Controlled Trial Comparing Imeglimin vs. · Phase 4 · not yet recruiting
- NCT07534943 — Effectiveness of Oleanolic Acid as Intracanal Medicament on Infectious/Inflammatory Contents in Teeth With Apical Period · NA · active not recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07052526 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Mansoura University
- Last refreshed: 9 July 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07052526.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing