Last reviewed · How we verify
NCT07051694: TaVNS-Sepsis
Transcutaneous Auricular Vagus Nerve Stimulation as Adjuvant Treatment for Sepsis Patients
NA trial testing taVNS in Sepsis in 60 participants. Currently enrolling.
31 October 2026
Quick facts
| Lead sponsor | Third Military Medical University |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | treatment |
| Enrollment | 60 |
| Start date | 27 February 2025 |
| Primary completion | 31 October 2026 |
| Estimated completion | 31 December 2026 |
| Sites | 1 location across China |
Drugs / interventions tested
- taVNS
- sham-taVNS
Conditions studied
- Sepsis — all drugs for Sepsis →
Sponsor
Third Military Medical University
Who can join
Adults 18 to 80, any sex, with Sepsis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goals of this randomized clinical trial are to investigate the effects of transcutaneous auricular vagus nerve stimulation (taVNS) combined with standard intensive care on systemic organ function in septic patients, and exploring its potential mechanisms for improving overall outcomes in sepsis.The main question it aims to answer is whether taVNS can reduce the severity of sepsis patients by ameliorating systemic inflammation.Participants will receive standard intensive care treatment and be randomized to receive the taVNS or sham taVNS as adjuvant treatment twice a day for 7 consecutive days. Several evaluations will be done before and after the intervention.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07051694
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of taVNS
Trials testing the same drug.
- NCT07272954 — Effects of Ultrasound-Guided Stellate Ganglion Block and Transcutaneous Auricular Vagus Nerve Stimulation on Sleep Quali · NA · not yet recruiting
- NCT07517237 — taVNS + CCT for Neurocognitive Rehab · NA · recruiting
- NCT07049952 — BabySTrong II taVNS Feeding Trial · Phase 2, PHASE3 · recruiting
- NCT07063446 — sTMS Combined With CIMT and taVNS In Infants With Hemiplegia · NA · recruiting
- NCT06998784 — Effect of Transcutaneous Auricular Vagal Nerve Stimulation on Acute Pancreatitis · NA · completed
Other recruiting trials for Sepsis
Currently open trials in the same condition.
- NCT07507877 — Infraclavicular Axillary Vein Collapsibility Index as a Predictor of Fluid Responsiveness · recruiting
- NCT07154615 — Assessing Immune Dysfunction in Sepsis · recruiting
- NCT07419802 — OxiCLEAR (Oxiris Cytokines and Endotoxin Adsorption Rate) Study · recruiting
- NCT07351344 — African Survey on Sepsis Knowledge (ASK) · recruiting
- NCT07448805 — Accuracy and Safety of the Syai Tag System for Continuous Glucose Monitoring in Intensive Internal Care Unit · NA · recruiting
Other Third Military Medical University trials
Trials by the same sponsor.
- NCT07536477 — High-flow Nasal Cannula Oxygen Therapy Versus Conventional Oxygen Therapy in High-altitude Pulmonary Edema · NA · not yet recruiting
- NCT07488507 — Diagnostic Value and Safety of Combined Biopsy for Mediastinal Metastasis of Lung Cancer · NA · recruiting
- NCT07277907 — Efficacy and Safety of Lubiprostone in the Treatment of Slow Transit Constipation · Phase 3 · recruiting
- NCT04557995 — Erythrocytapheresis for Chronic Mountain Sickness · NA · recruiting
- NCT07036588 — PARLAR-02 Trial：Modified Transanal Drainage Tube Use for Preventing Anastomotic Leakage · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07051694 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Third Military Medical University
- Last refreshed: 4 July 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07051694.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing