Prospective Multicenter Cohort Study for the Development and Evaluation of Risk Stratification Tools for Lung Cancers and Their Postoperative Recurrences Using Multimodal Clinical, Radiological, Tissue and Longitudinal Biological Phenotyping Among People at Risk of Lung Cancer (LUCA-pi COHORT)

NCT07042867 NA NOT_YET_RECRUITING

Interventional study with minimal risks and constraints, involving annual assessment of the prevalence and incidence of lung cancer using low-dose contrast-free thoracic CT scans, immunological, inflammatory, metabolic, blood nucleic acid and digestive microbiota profiles; systematic proposal of smoking cessation for active smokers, or assistance in maintaining cessation This is a prospective validation study of risk stratification tools still under development. The results of this study will be used to design medical devices (software integrating risk stratification tools), which will then be evaluated as part of subsequent Clinical Investigations.

Details

Lead sponsor	Assistance Publique Hopitaux De Marseille
Phase	NA
Status	NOT_YET_RECRUITING
Enrolment	900
Start date	Tue Jul 15 2025 00:00:00 GMT+0000 (Coordinated Universal Time)
Completion	Sat Jan 15 2028 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

• Lung Cancer (Diagnosis)

Interventions

• biobanking
• low dose scan