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NCT07042204
Effectiveness of E-prf Alone and in Combination With Bioactive Glass Nanoparticles in Grade II Furcation Defects
NA trial testing Group I (extended platelet-rich fibrin) in Furcation Defects in 30 participants. Completed in 3 August 2025.
3 June 2025
Quick facts
| Lead sponsor | Merna Nasser Mohamed Mostafa Ibrahim Elnahas |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 30 |
| Start date | 3 January 2024 |
| Primary completion | 3 June 2025 |
| Estimated completion | 3 August 2025 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Group I (extended platelet-rich fibrin)
- Group II (bioactive glass nanoparticles mixed with extended platelet-rich fibrin)
- Group III (bioactive glass nanoparticles and covered by a collagen membrane)
Conditions studied
- Furcation Defects — all drugs for Furcation Defects →
Sponsor
Merna Nasser Mohamed Mostafa Ibrahim Elnahas
Who can join
Adults 18 to 50, any sex, with Furcation Defects. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The aim of the study is to evaluate and compare the effectiveness of extended platelet-rich fibrin (ePRF) alone and in combination with bioactive glass nanoparticles in the treatment of grade II furcation defects clinically and radiographically.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT07042204
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Furcation Defects
Currently open trials in the same condition.
- NCT06270303 — Use of a Bone Substitute Material in the Surgical Therapy of Furcation Defects · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07042204 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Merna Nasser Mohamed Mostafa Ibrahim Elnahas
- Last refreshed: 13 January 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07042204.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing