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NCT07035262

Impact of Pre- and Post-operative Serum Metabolome Dynamics in Colorectal Resection Outcomes

Active, enrolled Last updated 25 June 2025
What this trial tests

trial testing serum metabolites in Colo-rectal Cancer in 400 participants. Participants enrolled and being followed up; not accepting new ones.

Timeline
1 January 2023
Primary endpoint
1 June 2025
1 September 2025

Quick facts

Lead sponsorDong Peng
StatusActive, enrolled
Study typeOBSERVATIONAL
Enrollment400
Start date1 January 2023
Primary completion1 June 2025
Estimated completion1 September 2025
Sites1 location across China

Drugs / interventions tested

Conditions studied

Sponsor

Dong Peng

Who can join

18 and older, any sex, with Colo-rectal Cancer. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The aim of this study is to systematically analyze the dynamic pattern of preoperative and postoperative serum metabolites in colorectal cancer patients through metabolomics technology, and to screen the key metabolites with statistical differences and explore their correlation with surgical interventions by combining the baseline characteristics of the patients with the perioperative clinical data; to further reveal the impact of surgery on the body's metabolic remodeling pattern, and to explore the potential biomarkers and regulatory pathways, providing a theoretical basis for elucidating the metabolic mechanism. Investigaters will further reveal the impact of surgery on metabolic remodeling, explore potential biomarkers and regulatory pathways, provide theoretical basis for elucidating the metabolic mechanism, and evaluate its clinical translational value (e.g., postoperative monitoring, targeted intervention, etc.), so as to lay the foundation for the subsequent basic research and precise treatment strategies.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

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Other recruiting trials for Colo-rectal Cancer

Currently open trials in the same condition.

Other Dong Peng trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

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