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Possible Mechanisms of Action of Magnetic Tape Through Its Application on the Epidermis
This study aims to evaluate the effects of a tape with magnetic particles versus a control kinesiotape on the skin's sensory and vascular responses in healthy volunteers. The tape is an elastic adhesive strip containing magnetic particles that may modulate sensory nerve endings. The hypothesis is that this magnetic tape can reduce pain and mechanical sensitivity and blood flow in the application area by stimulating cutaneous receptors. Thirty healthy participants will receive four different combinations of two types of tapes (magnetic vs. placebo) and two creams (anesthetic vs. moisturizing), applied to the lower back in a randomized crossover design. Sensory thresholds and blood flow will be measured at three body regions: close to the application site (lower back), a segmentally related area (posterior thigh), and an unrelated distant site (forearm). Measurements will include pressure pain threshold, mechanical sensitivity, and tactile detection, using standardized tools and Doppler ultrasound The study will help determine whether the effects of magnetic tape are local or systemic, whether they depend on skin receptor activation, and whether they can be blocked by topical anesthesia
Details
| Lead sponsor | Patricia Beltra Lopez |
|---|---|
| Phase | NA |
| Status | NOT_YET_RECRUITING |
| Enrolment | 30 |
| Start date | 2025-07 |
| Completion | 2026-01 |
Conditions
- Healthy Volunteers
Interventions
- Tape with mangetic particles
- Topical Anesthetic Cream
- Control KinesioTape
- Moisturizing Cream (control)
Primary outcomes
- Mechanical pain sensitivity (300g Von Frey monofilament) — Baseline (pre-intervention), Post-cream (immediately after cream removal), Mid-intervention (with tape on), and Immediate Post-intervention (immediately after tape removal) at each weekly visit (Visits 1-4)
Pain intensity will be assessed using a 300g Von Frey filament applied to the skin. Participants will report pain on an 11-point verbal Numeric Rating Scale (vNRS) from 0 (no pain) to 10 (worst imaginable pain). This measurement is performed in three regions (lumbar area, posterior thigh, and forearm) before and after each intervention. Higher NRS scores indicate greater mechanical pain sensitivity. Additionally, it will be applied on intervention location site to assess the cream effect and confirm the anesthetic effects