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NCT07032623
Neuromuscular Effects of Spinal Manipulation in Individuals Following Anterior Cruciate Ligament Reconstruction
NA trial testing Spinal Manipulation in Anterior Cruciate Ligament Reconstruction in 20 participants. Completed in 3 June 2025.
30 April 2025
Quick facts
| Lead sponsor | Universidad Rey Juan Carlos |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | basic science |
| Enrollment | 20 |
| Start date | 3 March 2025 |
| Primary completion | 30 April 2025 |
| Estimated completion | 3 June 2025 |
| Sites | 1 location across Portugal |
Drugs / interventions tested
- Spinal Manipulation
Conditions studied
- Anterior Cruciate Ligament Reconstruction — all drugs for Anterior Cruciate Ligament Reconstruction →
Sponsor
Universidad Rey Juan Carlos — full company profile →
Who can join
Adults 18 to 55, any sex, with Anterior Cruciate Ligament Reconstruction. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This single-blind, randomized controlled trial aims to investigate the effects of spinal manipulation on neuromuscular control in individuals with anterior cruciate ligament reconstruction during a single-leg vertical drop landing task. The intervention group will receive spinal manipulation, while the control group will not receive any therapeutic intervention. The main question it aims to answer is: • Can spinal manipulation induce changes in muscle activation, co-contraction magnitude, and biomechanical parameters during landing?
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Targeting neuromuscular deficits following anterior cruciate ligament reconstruction with spinal manipulation: A randomized controlled trial.
Paredes R, Crasto C, Montes AM, André A, et al · · 2026 · PMID 42208111 · DOI 10.1016/j.jelekin.2026.103177
Verify or expand the search:
- PubMed search for NCT07032623
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Spinal Manipulation
Trials testing the same drug.
- NCT06946979 — Clinical Study on the Use of Massage to Reconstruct the Function of Lumbar Stabilizer Muscles and Improve the "Muscle an · NA · not yet recruiting
- NCT06576739 — B Vitamin Supplementation to Chiropractic Management of Chronic LBP: Pilot Clinical Trial (VCLBP) · NA · not yet recruiting
- NCT06606795 — The Effects of Cervical and Thoracic Manipulation Therapy Applied to Weightlifting Athletes · NA · not yet recruiting
- NCT06673537 — Spinal Manipulation For Menstrual Symptoms and Sleep in Individuals With Primary Dysmenorrhea · NA · completed
- NCT06578208 — Comparison of the Effect of Spinal Manipulation by Gender · NA · completed
Other recruiting trials for Anterior Cruciate Ligament Reconstruction
Currently open trials in the same condition.
- NCT06357091 — ACL Reconstruction With Shark Screw® or Biocomposite-interference Screws · NA · recruiting
- NCT06858293 — Mental Imagery to Improve Quadriceps Strength Post Anterior Cruciate Ligament Reconstruction: a Feasibility Study · NA · recruiting
- NCT06493851 — The Effect of Hyperbaric Oxygen Therapy for Acceleration Recovery After Anterior Cruciate Ligament Reconstruction(ACLR) · NA · recruiting
- NCT06341192 — Comparison Between Combined ALLR With Single Bundle and Double Bundle Anterior Cruciate Ligament Reconstruction · NA · recruiting
- NCT06464705 — To Investigate the Effect of PEMF for Pateitns After Anterior Cruciate Ligament Reconstruction With Hamstring Autograft · NA · recruiting
Other Universidad Rey Juan Carlos trials
Trials by the same sponsor.
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- NCT07247760 — PATIENT SATISFACTION AND MASKING OF WHITE SPOT LESIONS AFTER HOME WHITENING WITH 10% CARBAMIDE PEROXIDE · NA · enrolling by invitation
- NCT06968676 — Mixed Reality for Upper Limb Rehabilitation in People With Multiple Sclerosis (VIRTUALDOMUS) · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07032623 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Universidad Rey Juan Carlos
- Last refreshed: 27 June 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07032623.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing