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NCT07028099
A Study on the Clinical Use of a New Expandable OLIF Cage With Posterior Bone Grafting in Lumbar Spine Surgery
NA trial testing Expandable OLIF cage with posterior bone grafting in Lumbar Spondylolisthesis in 340 participants. Not yet recruiting.
1 June 2026
Quick facts
| Lead sponsor | The Affiliated Hospital of Qingdao University |
|---|---|
| Phase | NA |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 340 |
| Start date | 10 June 2025 |
| Primary completion | 1 June 2026 |
| Estimated completion | 31 May 2027 |
Drugs / interventions tested
- Expandable OLIF cage with posterior bone grafting
- Conventional OLIF cage
Conditions studied
- Lumbar Spondylolisthesis — all drugs for Lumbar Spondylolisthesis →
- Degenerative Lumbar Scoliosis — all drugs for Degenerative Lumbar Scoliosis →
- Lumbar Disc Herniation — all drugs for Lumbar Disc Herniation →
- Lumbar Spinal Stenosis — all drugs for Lumbar Spinal Stenosis →
Sponsor
The Affiliated Hospital of Qingdao University
Who can join
Adults 40 to 80, any sex, with Lumbar Spondylolisthesis or Degenerative Lumbar Scoliosis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This clinical trial aims to evaluate the safety and effectiveness of a novel expandable OLIF (Oblique Lateral Interbody Fusion) cage with posterior bone grafting in patients with lumbar degenerative diseases. OLIF is a minimally invasive spinal surgery technique that restores intervertebral height and relieves nerve compression by placing a cage into the disc space. The new device allows surgeons to adjust the height of the cage during surgery and deliver bone grafts through a special channel after expansion. This study compares the outcomes of patients receiving the new cage versus those treated with a conventional OLIF cage. The trial will assess pain relief, functional improvement, spinal stability, fusion success, and potential complications. Radiological images and patient-reported scores (like VAS and ODI) will be collected over 12 months. The study includes patients aged 40 to 80 with single-level lumbar spine disease who have not improved after at least 6 months of conservative treatment. This study will help determine whether the new expandable cage offers clinical advantages and better long-term outcomes for patients undergoing OLIF surgery.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07028099
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Lumbar Spondylolisthesis
Currently open trials in the same condition.
- NCT05029726 — Regional Anesthesia in Minimally Invasive Lumbar Spine Surgery · Phase 4 · recruiting
- NCT05945550 — Comparison of Complication Rates Between Initial and Re-operative Anterior Lumbar Interbody Fusion Surgery: Is There a D · active not recruiting
- NCT03570801 — SLIP II Registry: Spinal Laminectomy Versus Instrumented Pedicle Screw Fusion · NA · active not recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07028099 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by The Affiliated Hospital of Qingdao University
- Last refreshed: 19 June 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07028099.
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