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NCT07028021

Study on Water Turnover of the Chinese Population Based on Deuterium Dilution Method

Recruiting now Last updated 19 June 2025
What this trial tests

trial in Water Turnover in 300 participants. Currently enrolling.

Timeline
6 May 2025
Primary endpoint
30 June 2026
30 October 2026

Quick facts

Lead sponsorShenzhen Institutes of Advanced Technology ,Chinese Academy of Sciences
StatusRecruiting now
Study typeOBSERVATIONAL
Enrollment300
Start date6 May 2025
Primary completion30 June 2026
Estimated completion30 October 2026
Sites1 location across China

Conditions studied

Sponsor

Shenzhen Institutes of Advanced Technology ,Chinese Academy of Sciences

Who can join

18 and older, any sex, with Water Turnover or Population Water Requirements. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Water is essential for sustaining life and maintaining health. The human body relies on water to transport nutrients and waste products, lubricate joints, regulate body temperature, and preserve tissue structure. International research has shown that losing just 2% of body weight through water loss can impair physiological functions and reduce response capacity. Adequate water intake plays a crucial protective role in health: it helps regulate body weight, lowers the risk of chronic diseases such as cardiovascular and cerebrovascular conditions, and supports cognitive function. However, the common recommendation to drink eight cups of water per day lacks strong scientific evidence. Most national hydration guidelines are based on average population intake, and personalized water intake recommendations have yet to be fully developed. In this study, the investigators will use the deuterium dilution technique to measure water turnover in volunteers. Body composition will be assessed using the TANITA MC-780, while a seven-day fluid intake diary will track daily water consumption. Physical activity levels will be monitored using GT3 devices, and environmental data-including altitude, temperature, and humidity-will be collected based on participants' locations. The goal of this study is to collect comprehensive data on the physiological traits, environmental influences, and hydration needs of the Chinese population. This will allow for refinement and optimization of current prediction equations for water requirements. Ultimately, the investigators aim to develop a new, individualized water intake algorithm tailored to the Chinese population by quantifying the proportion of water intake relative to total water requirements.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

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