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NCT07025317: SMARTBRAIN
Spotting and Managing Adult Repeated Traumas in the Brain
NA trial testing Perceptual-cognitive in Brain Injury Traumatic Mild in 200 participants. Currently enrolling.
15 July 2025
Quick facts
| Lead sponsor | Université de Montréal |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | basic science |
| Enrollment | 200 |
| Start date | 1 March 2024 |
| Primary completion | 15 July 2025 |
| Estimated completion | 28 February 2027 |
| Sites | 3 locations across Canada |
Drugs / interventions tested
- Perceptual-cognitive
Conditions studied
- Brain Injury Traumatic Mild — all drugs for Brain Injury Traumatic Mild →
Sponsor
Université de Montréal — full company profile →
Who can join
60 and older, any sex, with Brain Injury Traumatic Mild. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Emerging evidence suggests that concussions (a type of mild traumatic brain injury; mTBIs) may cause chronic neurological disturbances with effects lasting beyond 20 years, changing brain structure and nearly doubling the risks of developing dementia into old age. Yet diagnoses remain notoriously difficult, gender differences are poorly understood, and negligible therapies exist to manage and treat these long-term effects. This project proposes using a combination of NeuroTracker (a promising software-based cognitive assessment and intervention for mild TBIs), with the latest MRI techniques and blood-based biomarkers of brain function, to provide unprecedented assessment sensitivity of long-term concussion effects, comparing older male and female adults, with and without a history of concussion. Additionally, NeuroTracker will be used as a therapeutic intervention to improve outcomes in adults with histories of concussion, with the combined assessments measuring efficacy pre-post training. This project aims to comprehensively understand the impacts of mild brain traumas into later life, via both physical and functional biomarkers of brain health. It will also validate the value of NeuroTracker as an accessible training intervention for recovering cognitive functions impacted by earlier-life concussions.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07025317
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Brain Injury Traumatic Mild
Currently open trials in the same condition.
- NCT06036147 — Concussion Health Improvement Program · NA · recruiting
- NCT06150196 — Brain Health & Wellness Classes for Veterans With Traumatic Brain Injury · NA · recruiting
Other Université de Montréal trials
Trials by the same sponsor.
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- NCT07259382 — Neuro-Inflammation in Extremity Trauma: Risk Verification in Elbow Trauma: The NERVE Study · not yet recruiting
- NCT07194629 — Pilot and Feasibility Study of Impact of SDF 38% Application on Oral Health of Elderly With Autonomy Loss · Phase 4 · not yet recruiting
- NCT06527274 — Effect of Defocus in Soft Contact Lenses on Internal Retinal Vascularization · NA · active not recruiting
- NCT06634264 — Comparison of Two Reeducation Methods in Children With Persistent Sleep Apnea, a Randomized Controlled Trial · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07025317 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Université de Montréal
- Last refreshed: 20 July 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07025317.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing