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NCT07023185
Cold and Compression After Total Knee Arthroplasty for Pain Attenuation: A Randomized, Controlled Trial
NA trial testing Cold and Compression in Primary Osteoarthritis Patients Scheduled for Total Knee Replacement Surgery in 90 participants. Currently enrolling.
1 June 2027
Quick facts
| Lead sponsor | Ochsner Health System |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 90 |
| Start date | 15 December 2025 |
| Primary completion | 1 June 2027 |
| Estimated completion | 1 June 2028 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Cold and Compression
- SOC (Standard of care) — full drug profile →
Conditions studied
- Primary Osteoarthritis Patients Scheduled for Total Knee Replacement Surgery — all drugs for Primary Osteoarthritis Patients Scheduled for Total Knee Replacement Surgery →
Sponsor
Ochsner Health System — full company profile →
Who can join
50 and older, any sex, with Primary Osteoarthritis Patients Scheduled for Total Knee Replacement Surgery. Patients with the condition only — healthy volunteers not accepted.
What's being measured
Primary outcomes are the specific endpoints the trial is designed to prove or disprove.
-
PROMIS Pain NRS subscale
Time frame: Enrollment to 6 months post-surgery
Compare pain score (Patient-Reported Outcomes Measurement Information System: PROMIS NRS Pain Subscale) between the control and cold/compression groups
Sponsor's own description
The purpose of this study is to compare pain score (Patient-Reported Outcomes Measurement Information System: PROMIS NRS Pain Subscale) between the control and cold/compression groups pre-surgically, daily after surgery for 14 days, then weekly after surgery for 3 months, and at 6 months post-surgery.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07023185
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Cold and Compression
Trials testing the same drug.
- NCT07516327 — Cold and Compression After Rotator Cuff Repair (RCR) · NA · recruiting
Other Ochsner Health System trials
Trials by the same sponsor.
- NCT07516327 — Cold and Compression After Rotator Cuff Repair (RCR) · NA · recruiting
- NCT07226973 — Gait After THA: Direct Anterior vs Manual Posterior vs Robotic Posterior · NA · recruiting
- NCT06920563 — Remote Postpartum Blood Pressure Monitoring and Cardiovascular Education · NA · recruiting
- NCT06613191 — Colonoscopy and Antiplatelet Therapy Trial · Phase 4 · not yet recruiting
- NCT05516641 — Prebiotics in Rectal Cancer · NA · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07023185 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Ochsner Health System
- Last refreshed: 1 April 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07023185.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing