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NCT07022730

Prophylactic Noradrenaline Infusion and Its Impact on Post-induction Hypotension

Completed NA Last updated 18 September 2025
What this trial tests

NA trial testing Noradrenaline 0.2 mcg/kg/min at 5 minutes before induction in Post Induction Hypotension in 80 participants. Completed in 17 September 2025.

Timeline
22 June 2025
Primary endpoint
17 September 2025
17 September 2025

Quick facts

Lead sponsorCairo University
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingdouble
Primary purposeprevention
Enrollment80
Start date22 June 2025
Primary completion17 September 2025
Estimated completion17 September 2025
Sites1 location across Egypt

Drugs / interventions tested

Conditions studied

Sponsor

Cairo University

Who can join

Adults 20 to 65, any sex, with Post Induction Hypotension or Sepsis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

researchers aim to evaluate the influence of prophylactic noradrenaline infusion on post-induction hypotension

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Preemptive noradrenaline infusion: a game-changer against post-induction hypotension in surgical sepsis: a randomized double blind trial.
    Helmy MA, Mostafa MS, Saber AT, Ali MA, et al · · 2026 · PMID 41965525 · DOI 10.1186/s12871-026-03783-2

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Trials by the same sponsor.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing