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NCT07022730
Prophylactic Noradrenaline Infusion and Its Impact on Post-induction Hypotension
NA trial testing Noradrenaline 0.2 mcg/kg/min at 5 minutes before induction in Post Induction Hypotension in 80 participants. Completed in 17 September 2025.
17 September 2025
Quick facts
| Lead sponsor | Cairo University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | prevention |
| Enrollment | 80 |
| Start date | 22 June 2025 |
| Primary completion | 17 September 2025 |
| Estimated completion | 17 September 2025 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Noradrenaline 0.2 mcg/kg/min at 5 minutes before induction — full drug profile →
Conditions studied
- Post Induction Hypotension — all drugs for Post Induction Hypotension →
- Sepsis — all drugs for Sepsis →
Sponsor
Cairo University
Who can join
Adults 20 to 65, any sex, with Post Induction Hypotension or Sepsis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
researchers aim to evaluate the influence of prophylactic noradrenaline infusion on post-induction hypotension
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Preemptive noradrenaline infusion: a game-changer against post-induction hypotension in surgical sepsis: a randomized double blind trial.
Helmy MA, Mostafa MS, Saber AT, Ali MA, et al · · 2026 · PMID 41965525 · DOI 10.1186/s12871-026-03783-2
Verify or expand the search:
- PubMed search for NCT07022730
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07022730 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Cairo University
- Last refreshed: 18 September 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07022730.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing