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NCT07021287
Effect of Different Cold Therapy Programs in Patients Received Total Knee Arthroplasty Operation
NA trial testing mixed ice and water, continuous ice application in Total Knee Arthroplasty in 260 participants. Currently enrolling.
1 April 2026
Quick facts
| Lead sponsor | The Fourth Affiliated Hospital of Zhejiang University School of Medicine |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | single |
| Primary purpose | supportive care |
| Enrollment | 260 |
| Start date | 6 July 2024 |
| Primary completion | 1 April 2026 |
| Estimated completion | 1 June 2026 |
| Sites | 2 locations across China |
Drugs / interventions tested
- mixed ice and water, continuous ice application
- mixed ice and water, intermittent ice compress
- full ice, continuous ice compress
- full ice, intermittent ice compress
Conditions studied
- Total Knee Arthroplasty — all drugs for Total Knee Arthroplasty →
Sponsor
The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Who can join
18 and older, any sex, with Total Knee Arthroplasty. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study conducts clinical experiments on the form, temperature, frequency and other issues of cooling therapy, so as to provide scientific evidence for the practice of cooling therapy and improve the comfort and effect of cooling therapy, so as to achieve the goal of improving service and patient experience proposed by the National Health Commission.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07021287
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Total Knee Arthroplasty
Currently open trials in the same condition.
- NCT07524387 — Femoral Triangle Block vs Adductor Canal Block on Early Quadriceps Function After Total Knee Arthroplasty · NA · recruiting
- NCT07511842 — REST-Knee: A Pilot RCT of 72-Hour Knee Immobilization and Pain Outcomes · NA · recruiting
- NCT07324954 — Methylene Blue in Total Knee Arthroplasty (TKA) · Phase 1 · recruiting
- NCT07336160 — ERAS-Based Preoperative Nutrition and Fasting in Total Knee Arthroplasty · NA · recruiting
- NCT07371390 — Minimal Sedation During Knee Replacement Surgery · NA · recruiting
Other The Fourth Affiliated Hospital of Zhejiang University School of Medicine trials
Trials by the same sponsor.
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- NCT07301437 — RWS of of Liraglutide Alone and in Combination With Orlistat for Weight Loss in Overweight/Obese Patients. · Phase 4 · not yet recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07021287 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by The Fourth Affiliated Hospital of Zhejiang University School of Medicine
- Last refreshed: 13 June 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07021287.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing