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NCT07013942
Additional Effects of Dry Needling With PNF on Spasticity and Functional Performance in Stroke
NA trial testing Dry Needling Group in Spasticity in 30 participants. Completed in 15 April 2025.
15 March 2025
Quick facts
| Lead sponsor | Foundation University Islamabad |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 30 |
| Start date | 12 September 2024 |
| Primary completion | 15 March 2025 |
| Estimated completion | 15 April 2025 |
| Sites | 1 location across Pakistan |
Drugs / interventions tested
- Dry Needling Group
- Sham Needling Group
Conditions studied
- Spasticity — all drugs for Spasticity →
- Dry Needling — all drugs for Dry Needling →
- Functional Performance — all drugs for Functional Performance →
Sponsor
Foundation University Islamabad
Who can join
60 and older, any sex, with Spasticity or Dry Needling. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Stroke is a prevalent cause of long-term disability, with a rising global incidence. Stroke patients commonly experience impaired balance and trunk control, which limits their daily activities and quality of life. Spasticity is the result of upper motor neuron lesion in which the reflex arc is spared, however there is a lesion to the descending pathways of the spinal cord, which leads to the hyper excitability of the alpha motor neurons. Spasticity is a form of velocity dependent hypertonia. When dry needle is applied it induces relaxation in the muscle by increasing the distance between the z lines in the sarcomere and reduces the overlapping of contractile proteins, which ultimately leads to relaxation in the muscle. Dry needling also reduces the firing of the afferent pathways from the local muscle to the spinal cord reducing the excitability of the alpha motor neurons this leads to reduce spasticity. A randomized control trial will be conducted in multidisciplinary lab of FUCP, department of physical medicine and rehabilitation of Fauji Foundation Hospital on the sample of 30 participants. The subjects will be randomized into two groups by sealed opaque envelope method. A treatment over the course of 6 weeks will be provided. Interventional group will be receiving dry needling in addition to Proprioceptive Neuromuscular Facilitation while the control group will receive sham needling in addition to Proprioceptive Neuromuscular Facilitation. Exercise training would be done for a total of 6 weeks, with needling twice a week, the session will last 30- 50 minutes. Using SPSS version 21 would do analysis. Ethical approval will be obtained from ERC of FUSH. Informed written consent will be obtained from all participants.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT07013942
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Related trials
Other trials of Dry Needling Group
Trials testing the same drug.
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- NCT03946995 — Dry Needling Versus Graston Technique in Active Myofascial Trigger Points on Upper Trapezius · NA · completed
Other recruiting trials for Spasticity
Currently open trials in the same condition.
- NCT05926596 — Leg Stretching Using an Exoskeleton on Demand for People With Spasticity · NA · recruiting
- NCT07466823 — Classification of Upper and Lower Limb Spasticity Patterns and Their Impact on Quality of Life in Patients With Multiple · recruiting
- NCT07273591 — Effects of Low-level Laser Therapy on Spasticity and Gait Parameters in Chronic Stroke Patients With Spastic Plantar Fle · NA · recruiting
- NCT06811142 — Early Botulinum Toxin for Muscle Stiffness Reduction in First-Time Stroke Patients: Improving Recovery and Independence · EARLY_PHASE1 · active not recruiting
- NCT06782464 — Upper Limb Nerve Cryoneurolysis is Non Inferior to the Usual Care and Has Therapeutic Add Value in Dealing With Shoulder · NA · recruiting
Other Foundation University Islamabad trials
Trials by the same sponsor.
- NCT07485777 — Comparative Evaluation of Topical 30% Metformin and Kligman's Regimen in Women With Melasma · NA · not yet recruiting
- NCT07495748 — Comparative Evaluation of Topical Metformin and Topical Tranexamic Acid in Melasma · NA · not yet recruiting
- NCT07519174 — A Randomized Controlled Trial Comparing the Effectiveness and Safety of Topical Tacrolimus 0.03% Versus Crisaborole 2% i · NA · not yet recruiting
- NCT07526051 — Effects of Autogenic Inhibition Versus Reciprocal Inhibition in Individuals With Lower Cross Syndrome · NA · recruiting
- NCT07526012 — Comparative Effects Of Post Isometric Relaxation Versus Active Isolated Stretch In Patients With Piriformis Syndrome · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07013942 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Foundation University Islamabad
- Last refreshed: 10 June 2025
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