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NCT07010341
Quantitative Intra-operative Assessment of Parathyroid Perfusion Using Indocyanine Green (ICG) Fluorescence Imaging
trial testing ntra-operative Indocyanine Green (ICG) Fluorescence Quantification in Thyroid Surgery in 210 participants. Currently enrolling.
30 November 2025
Quick facts
| Lead sponsor | Fujian Medical University |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 210 |
| Start date | 1 May 2025 |
| Primary completion | 30 November 2025 |
| Estimated completion | 31 May 2026 |
| Sites | 2 locations across China |
Drugs / interventions tested
- ntra-operative Indocyanine Green (ICG) Fluorescence Quantification
Conditions studied
- Thyroid Surgery — all drugs for Thyroid Surgery →
Sponsor
Fujian Medical University
Who can join
Eligibility, any sex, with Thyroid Surgery. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This single-center, prospective, three-phase observational cohort quantifies the relationship between indocyanine green (ICG) fluorescence and early parathyroid function. Adult patients scheduled for unilateral thyroid lobectomy with autotransplantation of the ipsilateral inferior parathyroid gland are enrolled. After intravenous ICG 25 µg/kg, peak fluorescence of the superior parathyroid gland and the common carotid artery (CCA) is recorded at 60-120 seconds to calculate the ratio R = PTG/CCA. Serum parathyroid hormone (PTH) is measured 30 minutes post-operatively. A derivation cohort (\~120 patients) generates R-based thresholds for in-situ preservation versus autotransplantation, which are prospectively validated in an independent cohort (60 patients) together with decision-curve analysis of clinical net benefit.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
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Related trials
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Currently open trials in the same condition.
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- NCT06838728 — The Effect of the Application of Head Mounted Magnifying Glasses on Postoperative PTH Changes in Thyroid Surgery: Stage · NA · active not recruiting
Other Fujian Medical University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07010341 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Fujian Medical University
- Last refreshed: 15 July 2025
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