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NCT07003347: REACH
Study to Investigate the Efficacy and Safety of SC0023, in Adults With Refractory or Unexplained Chronic Cough
NA trial testing oral spray of MgCl2 in Chronic Cough in 7 participants. Completed in 30 August 2025.
30 July 2025
Quick facts
| Lead sponsor | Kholood Altassan |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | quadruple |
| Primary purpose | treatment |
| Enrollment | 7 |
| Start date | 19 December 2024 |
| Primary completion | 30 July 2025 |
| Estimated completion | 30 August 2025 |
| Sites | 1 location across Saudi Arabia |
Drugs / interventions tested
- oral spray of MgCl2
- Saline
Conditions studied
- Chronic Cough — all drugs for Chronic Cough →
Sponsor
Kholood Altassan
Who can join
Adults 18 to 80, any sex, with Chronic Cough. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This is a randomized, double-blind, placebo controlled cross-over study to investigate the efficacy and safety of SC0023 (an oral spray of magnesium based alkaline hypertonic divalent salt) in adults with refractory or unexplained chronic cough over 14 days. Approximately 20 participants being enrolled and randomized into the study.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT07003347
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Chronic Cough
Currently open trials in the same condition.
- NCT07488598 — Efficacy of Behavioral Therapy for Chronic Refractory Cough · NA · recruiting
- NCT06542484 — The Real-world Treatment Satisfaction by Gefapixiant in RCC · NA · recruiting
- NCT05813223 — Effect of Gefapixant on Cough-related Brain Activity in Patients With Chronic Cough · EARLY_PHASE1 · recruiting
- NCT06286163 — Neuroinflammatory Interactions of ATP and P2X3 Receptor in the Airways of Chronic Cough Patients · recruiting
- NCT05362097 — Analysis of the Reliability and Validity of the Chinese Version of CC-QoL · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07003347 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Kholood Altassan
- Last refreshed: 21 January 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07003347.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing