Feasibility of Direct Oral Challenges in Private Practice Setting for the Evaluation of Mild Delayed Reactions to Beta-lactams in Children (Betalactaville)

NCT07002814 RECRUITING

The purpose of this study is to demonstrate the feasibility of direct oral challenge performed in private practice setting for children with suspected benign delayed allergy to beta-lactams. The results of this study could help establish recommendations for conducting direct oral challenge in primary care settings to delabeling children with benign delayed reactions to beta-lactams.

Details

Lead sponsor	Assistance Publique - Hôpitaux de Paris
Status	RECRUITING
Enrolment	200
Start date	2026-06
Completion	2027-06

Conditions

• Allergy

Primary outcomes

• Feasibility of direct oral challenge (DOC) for beta-lactam allergy assessment — Day 14
  Demonstrate the feasibility of direct oral challenges (DOCs) performed in private medical practices for the evaluation of delayed and benign reactions to beta-lactams in children by collecting the amount of positive and negative DOC results and benign reactions description.

Countries

France