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NCT07000448
Optimal Ventilation Strategies in Laparoscopic Hysterectomy
NA trial testing Dynamic compliance guided individualized positive end-expiratory pressure titration strategy in Recruitment Maneuver in 113 participants. Completed in 26 June 2024.
25 April 2024
Quick facts
| Lead sponsor | Bakirkoy Dr. Sadi Konuk Research and Training Hospital |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | supportive care |
| Enrollment | 113 |
| Start date | 9 December 2022 |
| Primary completion | 25 April 2024 |
| Estimated completion | 26 June 2024 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Dynamic compliance guided individualized positive end-expiratory pressure titration strategy
- standardized 5 PEEP
Conditions studied
- Recruitment Maneuver — all drugs for Recruitment Maneuver →
- Individualized PEEP — all drugs for Individualized PEEP →
- Total Hysterectomy — all drugs for Total Hysterectomy →
- Postoperative Pulmonary Complications — all drugs for Postoperative Pulmonary Complications →
Sponsor
Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Who can join
Adults 18 to 85, female only, with Recruitment Maneuver or Individualized PEEP. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The aim of this study was to investigate whether individualized PEEP application improves respiratory function and reduces the incidence of postoperative pulmonary complications (PPCs) in patients undergoing laparoscopic total hysterectomy. Investigators hypothesized that individualized PEEP would improve pulmonary oxygenation and reduce the incidence of postoperative pulmonary complications.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT07000448
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Dynamic compliance guided individualized positive end-expiratory pressure titration strategy
Trials testing the same drug.
- NCT04169607 — Effect of Intraoperative Dynamic Compliance Guided Individualized Positive End-expiratory Pressure on Postoperative Atel · NA · completed
Other Bakirkoy Dr. Sadi Konuk Research and Training Hospital trials
Trials by the same sponsor.
- NCT07425379 — Prehabilitation in Breast Cancer Surgery · NA · not yet recruiting
- NCT07367321 — Comparison of Onlay Mesh Repair and Sublay Mesh Repair in Umbilical Hernia Surgery · NA · not yet recruiting
- NCT07077629 — Geriatric Patients Undergoing Gynaecological Cancer Surgery · completed
- NCT07000461 — Transcranial Doppler as a Predictor of Postoperative Cognitive Dysfunction Following Cardiopulmonary Bypass · recruiting
- NCT07295405 — Water Temperature and Bowel Cleansing Quality · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07000448 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Bakirkoy Dr. Sadi Konuk Research and Training Hospital
- Last refreshed: 22 September 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07000448.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing