NCT06998810 (CRESTMS) is a NA clinical trial of cerebellar rTMS in Multiple Sclerosis, sponsored by Ain Shams University.

Who is sponsoring NCT06998810?

NCT06998810 is sponsored by Ain Shams University.

What drugs are being tested in NCT06998810?

Interventions in NCT06998810: cerebellar rTMS.

What condition does NCT06998810 study?

NCT06998810 studies Multiple Sclerosis.

Is NCT06998810 still recruiting?

NCT06998810 is currently completed. Last updated 31 May 2025.

Last reviewed 2025-05-31 · How we verify

NCT06998810: CRESTMS

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Cerebellar High-Frequency rTMS in Balance of Multiple Sclerosis Patients

Completed NA Last updated 31 May 2025

What this trial tests

NA trial testing cerebellar rTMS in Multiple Sclerosis in 40 participants. Completed in 25 March 2025.

Timeline

25 February 2023

Primary endpoint
25 December 2024

25 March 2025

Quick facts

Lead sponsor	Ain Shams University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	40
Start date	25 February 2023
Primary completion	25 December 2024
Estimated completion	25 March 2025
Sites	1 location across Egypt

Drugs / interventions tested

cerebellar rTMS

Conditions studied

Multiple Sclerosis — all drugs for Multiple Sclerosis →

Sponsor

Ain Shams University

Who can join

Adults 18 to 60, any sex, with Multiple Sclerosis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Background: Multiple Sclerosis (MS) is a chronic autoimmune disease affecting the central nervous system (CNS), leading to progressive motor dysfunction and balance deficits. Objective: To investigate the impact of cerebellar rTMS in improving postural control, balance performance and functional ambulation in individuals with MS. Forty patients were randomly assigned to receive repetitive transcranial magnetic stimulation (rTMS) over the cerebellum to improve motor function and balance in 40 MS patients. Outcome measures, including the Expanded Disability Status Scale (EDSS), static posturography (COP measures), the International Cooperative Ataxia Rating Scale (ICARS), and the 10-Meter Walk Test (10MWT), were assessed before and after intervention.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other recruiting trials for Multiple Sclerosis

Currently open trials in the same condition.

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Other Ain Shams University trials

Trials by the same sponsor.

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT06998810 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Ain Shams University
Last refreshed: 31 May 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06998810.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing