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NCT06996262

Cardiometabolic Risk Factors and Processed Food

Completed Last updated 30 May 2025
What this trial tests

trial testing observational study in Cardiac Disease in 236 participants. Completed in 30 April 2024.

Timeline
1 March 2024
Primary endpoint
30 April 2024
30 April 2024

Quick facts

Lead sponsorIstanbul Bilgi University
StatusCompleted
Study typeOBSERVATIONAL
Enrollment236
Start date1 March 2024
Primary completion30 April 2024
Estimated completion30 April 2024
Sites1 location across Turkey (Türkiye)

Drugs / interventions tested

Conditions studied

Sponsor

Istanbul Bilgi University

Who can join

Adults 18 to 65, any sex, with Cardiac Disease or Cardiovascular Diseases. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Cardiovascular diseases (CVD) remain a primary cause of chronic disability and mortality globally, with cardiometabolic risk factors such as hypertension, dyslipidemia, obesity, and diabetes significantly contributing to their development. Poor nutrition is recognized as a modifiable key risk factor for CVD, representing a crucial area for prevention strategies. While current research often emphasizes overall dietary patterns and quality in CVD prevention, the spectrum of food processing, ranging from minimally processed to ultra-processed foods (UPFs), can profoundly influence diet quality. Ultra-processed foods, characterized by industrial processing techniques, additives, and special industrial ingredients, have been shown to potentially compromise the health benefits of food by reducing essential nutrients and bioactive compounds, introducing unhealthy elements, and altering food structures. Emerging epidemiological evidence links higher UPF consumption to an increased risk of obesity, hypertension, metabolic syndrome, and type 2 diabetes, with studies like the Framingham Offspring Study indicating a positive association with CVD incidence. Globally, UPF consumption is on the rise, constituting a significant portion of daily energy intake. In Turkey, data from the 2021 National Nutrition and Health Survey reveals that a substantial 58% of adults consume processed foods daily . This is particularly concerning given Turkey's high burden of CVD, which has been the leading cause of mortality for decades and is projected to increase further due to an aging population and rising rates of diabetes and obesity. Notably, Turkey has the highest rate of early myocardial infarction in Europe. Given the increasing consumption of UPFs and their potential health implications, especially in a country with a high prevalence of CVD like Turkey, understanding the relationship between dietary factors and cardiovascular health is critical. Therefore, this study aims to investigate the association between processed food intake and cardiometabolic risk factors among adult individuals in Türkiye.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Processed Food Consumption Based on the NOVA Classification Is Associated With Elevated Cardiometabolic Risk in Turkish Adults.
    Ozkan I, Ozlu Karahan T, Seven Avuk H. · · 2025 · PMID 41019184 · DOI 10.1002/fsn3.71014

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Other trials of observational study

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