Last reviewed · How we verify
NCT06990412: NEO
A Clinical Trial to Evaluate the Safety and Efficacy of an Implantable Wireless Brain-Computer Interface（BCI）System NEO in Patients With Tetraplegia
NA trial testing NEO in Tetraplegia in 32 participants. Not yet recruiting.
31 December 2025
Quick facts
| Lead sponsor | Neuracle Medical Technology(Shanghai) Co.,Ltd. |
|---|---|
| Phase | NA |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | other |
| Enrollment | 32 |
| Start date | 20 May 2025 |
| Primary completion | 31 December 2025 |
| Estimated completion | 20 May 2026 |
| Sites | 2 locations across China |
Drugs / interventions tested
- NEO
Conditions studied
- Tetraplegia — all drugs for Tetraplegia →
- Spinal Cord Injuries (SCI) — all drugs for Spinal Cord Injuries (SCI) →
Sponsor
Neuracle Medical Technology(Shanghai) Co.,Ltd.
Who can join
Adults 18 to 65, any sex, with Tetraplegia or Spinal Cord Injuries (SCI). Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
To evaluate the safety and efficacy of a Minimally Invasive Wireless Implantable Brain-Computer Interface (BCI) System NEO in patients with tetraplegia and to provide a basis for product registration. Through brain-computer interface alternative technology, patients can control the external equipment with brain signals to improve the patient's quality of life.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Review of Recent Advances in Implantable Brain-Computer Interfaces for the Restoration of Motor Function in Patients With Paralysis.
Yang D, Liu X, Hu J, Zhang W. · · 2026 · PMID 41978246 · DOI 10.12659/msm.951925
Verify or expand the search:
- PubMed search for NCT06990412
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Tetraplegia
Currently open trials in the same condition.
- NCT07058506 — Control Interfaces for Operating Assistive Devices · NA · recruiting
- NCT06511934 — Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia (BG-Tablet-01) · NA · recruiting
- NCT06288763 — Nerve Transfer to Improve Function in High Level Tetraplegia · recruiting
- NCT06094205 — Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia (BG-Speech-02) · NA · recruiting
- NCT05553457 — MyHand-SCI: An Active Hand Orthosis for Spinal Cord Injury · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06990412 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 25 May 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Neuracle Medical Technology(Shanghai) Co.,Ltd.
- Last refreshed: 25 May 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06990412.