NCT06989814 (SMART) is a NA clinical trial of Blood Product in Colorectal Neoplasms, sponsored by Erasmus Medical Center.

Who is sponsoring NCT06989814?

NCT06989814 is sponsored by Erasmus Medical Center.

What drugs are being tested in NCT06989814?

Interventions in NCT06989814: Blood Product.

What condition does NCT06989814 study?

NCT06989814 studies Colorectal Neoplasms, Colorectal Neoplasms Malignant, Colorectal Neoplasms, Hereditary Nonpolyposis, Hereditary Nonpolyposis Colon Cancer.

Is NCT06989814 still recruiting?

NCT06989814 is currently recruiting now. Last updated 11 August 2025.

Last reviewed 2025-08-11 · How we verify

NCT06989814: SMART

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Smart Measurement of Circulating Tumor DNA

Recruiting now NA Last updated 11 August 2025

What this trial tests

NA trial testing Blood Product in Colorectal Neoplasms in 50 participants. Currently enrolling.

Timeline

16 May 2025

Primary endpoint
1 October 2026

1 February 2027

Quick facts

Lead sponsor	Erasmus Medical Center
Phase	NA
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	screening
Enrollment	50
Start date	16 May 2025
Primary completion	1 October 2026
Estimated completion	1 February 2027
Sites	2 locations across Netherlands

Drugs / interventions tested

Blood Product — full drug profile →

Conditions studied

Colorectal Neoplasms — all drugs for Colorectal Neoplasms →
Colorectal Neoplasms Malignant — all drugs for Colorectal Neoplasms Malignant →
Colorectal Neoplasms, Hereditary Nonpolyposis — all drugs for Colorectal Neoplasms, Hereditary Nonpolyposis →
Hereditary Nonpolyposis Colon Cancer — all drugs for Hereditary Nonpolyposis Colon Cancer →

Sponsor

Erasmus Medical Center

Who can join

18 and older, any sex, with Colorectal Neoplasms or Colorectal Neoplasms Malignant. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The goal of this study is to develop a blood-test which can detect colorectal cancer in early stages. Participants will be asked to take an extra blood test, which will be analyzed further in the lab.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Clinical Applications of Liquid Biopsy in Colorectal Cancer: A Focus on Registered Clinical Trials.
Garcia-Pelaez J, Yáñez Y, Aupí M, Lázaro M, et al · · 2026 · PMID 42194957 · DOI 10.3390/genes17050500
Liquid biopsy biomarkers for early detection of gastrointestinal cancers: Current landscape and emerging technologies.
Anees M, Sherry C, Park HY, Grayhack EE, et al · · 2026 · PMID 41866828 · DOI 10.1002/ctm2.70594

Verify or expand the search:

Other trials of Blood Product

Trials testing the same drug.

NCT07210918 — Serum Trace Element Levels in Some Gynecological Diseases · NA · completed
NCT07240142 — Neurotransmitter Levels in Children With Specific Learning Disorder · NA · completed

Other recruiting trials for Colorectal Neoplasms

Currently open trials in the same condition.

NCT06983639 — Randomized Trial Comparing Fecal Testing (FIT) to Colonoscopy for Post-polypectomy Surveillance · NA · recruiting
NCT07222800 — Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult · Phase 3 · recruiting
NCT07239479 — DEXDES Trial: Dexmedetomidine-Desflurane Combination in Laparoscopic Colectomy · NA · recruiting
NCT07262840 — Health Behavior Change in High-Risk Colorectal Cancer Individuals · NA · recruiting
NCT07257653 — The Safety and Efficacy of Cetuximab Beta Plus Fruquintinib With or Without Immune Checkpoint Inhibitorrs in First-line · Phase 2 · recruiting

Other Erasmus Medical Center trials

Trials by the same sponsor.

NCT07406269 — Clinical Evaluation of AI Decision Support for Early Rehabilitation After Surgery · NA · not yet recruiting
NCT07402109 — CBCT Guided Markerless SBRT for Renal Cell Cancer · NA · recruiting
NCT07383194 — Prediction Models for LDLT Outcomes · not yet recruiting
NCT07426575 — Evaluating the Usability of New Dialysis Bags · not yet recruiting
NCT07329296 — The Regenerative Capacity of the Donor Liver After Living Donor Liver Transplantation: an Ambidirectional Cohort Study · enrolling by invitation

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT06989814 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Erasmus Medical Center
Last refreshed: 11 August 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06989814.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing