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NCT06989632
Total Lumbar Disc Prosthesis and Subsequent Work Activity at at Least Five Years After Total Lumbar Disc Replacement
trial testing We want to know the work and sport activities that our patients are able to undertake after a total lumbar disc replacement in Lumbar Disc Degeneration in 150 participants. Currently enrolling.
1 September 2025
Quick facts
| Lead sponsor | University of Valencia |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 150 |
| Start date | 1 January 2006 |
| Primary completion | 1 September 2025 |
| Estimated completion | 1 September 2025 |
| Sites | 1 location across Spain |
Drugs / interventions tested
- We want to know the work and sport activities that our patients are able to undertake after a total lumbar disc replacement
Conditions studied
- Lumbar Disc Degeneration — all drugs for Lumbar Disc Degeneration →
- Lumbar Disc Disease — all drugs for Lumbar Disc Disease →
- Sciatica — all drugs for Sciatica →
- Lumbar Disc Herniation — all drugs for Lumbar Disc Herniation →
Sponsor
University of Valencia
Who can join
18 and older, any sex, with Lumbar Disc Degeneration or Lumbar Disc Disease. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Lumbosciatica is a very prevalent pathology. When conservative treatments fail, surgery should be considered. The traditional surgical treatment is lumbar arthrodesis. The vast majority of patients who undergo spinal fusion cannot return to their same job and a good number of them never work again. Another form of treatment for lumbosciatica is the implantation of a lumbar disc prosthesis. This technique preserves the mobility of the lumbar area that has been operated on. This allows for a greater return to work and a higher percentage of those who return to the same job. This study aims to quantify how many of the patients who have had a lumbar disc prosthesis implanted in the last twenty years have returned to their same job, how many have had to change their jobs, and how many have not returned to work and are now totally or completely disabled from work.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Tissue engineering strategies for treating intervertebral disc degeneration.
Nie G, Liu W, Zeng F, Hu J, et al · · 2025 · cited 2× · PMID 40727644 · DOI 10.3389/fbioe.2025.1582189 -
Long-term outcomes of total lumbar disc prosthesis: Sustained pain relief.
Vanaclocha V, Jordá-Gómez P, Saiz-Sapena N, Martínez-Leon J, et al · · 2025 · PMID 41280305 · DOI 10.1016/j.xnsj.2025.100813
Verify or expand the search:
- PubMed search for NCT06989632
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Lumbar Disc Degeneration
Currently open trials in the same condition.
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- NCT07085247 — The Role of Cutibacterium Acnes in the Development of Degenerative Lumbar Intervertebral Disc Disease · recruiting
- NCT07127380 — Comparison of Clinical Outcomes, Complications Rate and Treatment Costs of Mini-TLIF and MIDLIF in the Treatment of Disc · NA · recruiting
Other University of Valencia trials
Trials by the same sponsor.
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- NCT07471555 — Vascular Access and Intraosseus · NA · enrolling by invitation
- NCT07463066 — Long-Term Effectiveness of Pain Neuroscience Education in Women With Genito-Pelvic Pain/Penetration Disorder. · not yet recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06989632 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Valencia
- Last refreshed: 25 May 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06989632.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing