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NCT06988722
Laser Photobiomodulation After Dental Implant Surgery: A Comparison of 650 nm and 810 nm Diode Lasers
NA trial testing 650 nm Diode Laser PBM in Postoperative Pain in 60 participants. Completed in 29 June 2024.
2 June 2024
Quick facts
| Lead sponsor | National Institute of Laser Enhanced Sciences |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 60 |
| Start date | 17 August 2023 |
| Primary completion | 2 June 2024 |
| Estimated completion | 29 June 2024 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- 650 nm Diode Laser PBM
- 810 nm Diode Laser PBM
- Sham Laser PBM
Conditions studied
- Postoperative Pain — all drugs for Postoperative Pain →
- Dental Implant — all drugs for Dental Implant →
Sponsor
National Institute of Laser Enhanced Sciences
Who can join
Adults 20 to 65, any sex, with Postoperative Pain or Dental Implant. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this clinical trial is to evaluate the effectiveness of laser light therapy, known as photobiomodulation (PBM), in reducing pain after dental implant surgery. The study involves adult patients receiving a single dental implant in the upper posterior (back) area of the mouth. Participants are randomly assigned to receive PBM using either a 650 nm red diode laser, an 810 nm infrared diode laser, or a sham (inactive) laser. The study aims to assess whether PBM therapy can reduce pain during the first three days after surgery, decrease the need for pain medication, and improve oral health-related quality of life (OHRQoL). PBM is applied immediately after surgery and again within 48 hours. Pain intensity is measured at multiple time points (2, 6, 12, 24, 48, and 72 hours), analgesic use is recorded, and OHRQoL is evaluated using a standardized questionnaire.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Analgesic and OHRQoL Outcomes of 650 nm vs 810 nm Diode Laser Photobiomodulation After Dental Implant Placement: A Randomized Controlled Trial
Abdussalam MMY, Adham ZZA, Saeed-ur-Rahman R, Zaky AA. · · 2025 · DOI 10.21203/rs.3.rs-6858207/v1
Verify or expand the search:
- PubMed search for NCT06988722
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Currently open trials in the same condition.
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- NCT07413055 — Comparative Efficacy Of 4 mg VS. 8 mg Submucosal Dexamethasone In Postoperative Pain Management After Dental Implant Sur · Phase 3 · recruiting
- NCT07496086 — External Oblique Intercostal Block Versus Transversus Abdominis Plane Combined With Rectus Sheath Block on Postoperative · NA · recruiting
- NCT07396545 — External Oblique Intercostal Block Versus Erector Spinae Plane Block on Postoperative Pain in Laparoscopic Radical Gastr · NA · recruiting
Other National Institute of Laser Enhanced Sciences trials
Trials by the same sponsor.
- NCT07069764 — Efficacy of Photobiomodulation Therapy Using 980nm Versus 635nm Diode Lasers for Treatment of Myofascial Pain · NA · completed
- NCT04789629 — Effect of Low Level Laser Therapy on Hamstring Muscle Tightness and Calf Muscle Spasticity in Cerebral Palsy Children. · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06988722 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by National Institute of Laser Enhanced Sciences
- Last refreshed: 25 May 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06988722.
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