Last reviewed · How we verify
NCT06988111
Management of Post-operative Respiratory Failure by Using NIV and High Velocity Nasal Insufflation (HVNI)
NA trial testing BIPAP in Respiratory Failure Without Hypercapnia in 180 participants. Not yet recruiting.
1 July 2026
Quick facts
| Lead sponsor | Assiut University |
|---|---|
| Phase | NA |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | supportive care |
| Enrollment | 180 |
| Start date | 1 July 2025 |
| Primary completion | 1 July 2026 |
| Estimated completion | 1 December 2026 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- BIPAP
- Vapotherm
Conditions studied
- Respiratory Failure Without Hypercapnia — all drugs for Respiratory Failure Without Hypercapnia →
- Respiratory Failure With Hypercapnia — all drugs for Respiratory Failure With Hypercapnia →
- Postoperative Respiratory Complication — all drugs for Postoperative Respiratory Complication →
Sponsor
Assiut University
Who can join
18 and older, any sex, with Respiratory Failure Without Hypercapnia or Respiratory Failure With Hypercapnia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Postoperative respiratory failure (PORF) remains a critical driver of morbidity, mortality, and incremental care costs in surgical populations. Traditional escalation often involves invasive mechanical ventilation, which is associated with ventilator-associated pneumonia (VAP), prolonged intensive care unit (ICU) stays, and increased resource burden.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06988111
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of BIPAP
Trials testing the same drug.
- NCT07193017 — The Effect of BIPAP on Diaphragmatic Function · not yet recruiting
- NCT06567587 — Dexmedtomodine Effect on Agitated Psychotic Patients Suffer COPD · completed
- NCT04205422 — Effect of Two Modes of Mechanical Ventilation on Metabolic Demands and Respiratory Mechanics · NA · unknown
Other recruiting trials for Respiratory Failure Without Hypercapnia
Currently open trials in the same condition.
- NCT07211529 — Intraoperative Paravertebral Block and Postoperative Complications · NA · recruiting
Other Assiut University trials
Trials by the same sponsor.
- NCT07423312 — Lead Exposure and Multiple Sclerosis · not yet recruiting
- NCT07234526 — Usage of Glucose Fluctuations as a Prognostic Marker in Septic Shock Patients · not yet recruiting
- NCT07273214 — Knowledge, Attitude and Practice of Third Trimester Pregnant Mothers Towards Self-Medication in Assiut, Egypt · not yet recruiting
- NCT07194863 — Efficacy of Essential Phospholipid Versus Betaine HCL/L-Glutamic Acid in MAFLD · not yet recruiting
- NCT07053709 — Screening for Hyperuricemia in Patients With Metabolic Associated Fatty Liver Disease (MAFLD) · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06988111 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Assiut University
- Last refreshed: 23 May 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06988111.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing