Last reviewed · How we verify
NCT06986902
Comparative Analysis of Postoperative Manometry Outcomes in Nissen vs Toupet Fundoplication
NA trial testing Laparoscopic Nissen Fundoplication in GERD - Gastro-Esophageal Reflux Disease in 20 participants. Completed in 15 March 2025.
15 March 2025
Quick facts
| Lead sponsor | Ain Shams University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 20 |
| Start date | 10 March 2024 |
| Primary completion | 15 March 2025 |
| Estimated completion | 15 March 2025 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Laparoscopic Nissen Fundoplication
- Laparoscopic Toupet fundoplication
Conditions studied
- GERD - Gastro-Esophageal Reflux Disease — all drugs for GERD - Gastro-Esophageal Reflux Disease →
Sponsor
Ain Shams University
Who can join
Adults 18 to 65, any sex, with GERD - Gastro-Esophageal Reflux Disease. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This randomized controlled trial investigates the effects of laparoscopic Nissen and Toupet fundoplication on postoperative esophageal manometry findings in patients with gastroesophageal reflux disease (GERD). The study, conducted at Ain Shams University Hospitals, involved 20 adult patients randomly assigned to undergo either procedure. Preoperative and postoperative high-resolution manometry (HRM) was used to assess lower esophageal sphincter (LES) pressure and esophageal motility.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Comparative study between the effect of Nissen fundoplication and Toupet fundoplication on postoperative manometry findings. A randomized control trial study.
Gadalla EAY, El Serafy ME, El Din Abd El Monaem AH, El Sayed EA, et al · · 2025 · PMID 40858943 · DOI 10.1007/s00464-025-12112-6
Verify or expand the search:
- PubMed search for NCT06986902
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other Ain Shams University trials
Trials by the same sponsor.
- NCT07435493 — Fentanyl Versus Opioid Free Multimodal Analgesia for Perioperative Pain Control in Children With Mild to Moderate Obstru · NA · not yet recruiting
- NCT07482540 — Role of Dexmedatomidine Drug in Prevention of Atrial Fibrillations Post Mitral Valve Surgery · NA · not yet recruiting
- NCT07531030 — Posterior Pericapsular Deep Gluteal Block Combined With Pericapsular Nerve Group and Lateral Femoral Cutaneous Nerve Blo · NA · not yet recruiting
- NCT06839027 — Arterial to Central co2gap in Relation to Outcome After Cardiopulmonary Bypass · not yet recruiting
- NCT07516535 — DISS vs FANS in Suction-Assisted RIRS for Medium-Sized Renal Stones · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06986902 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Ain Shams University
- Last refreshed: 23 May 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06986902.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing