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NCT06985264
Dry Eye in Upper Eyelid Surgery: Muscle Versus Fat Removal
NA trial testing Upper Eyelid Blepharoplasty surgery in Eye Disorders in 142 participants. Enrolling by invitation.
1 September 2025
Quick facts
| Lead sponsor | Mersin Training and Research Hospital |
|---|---|
| Phase | NA |
| Status | ENROLLING BY INVITATION |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 142 |
| Start date | 1 May 2025 |
| Primary completion | 1 September 2025 |
| Estimated completion | 30 December 2025 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Upper Eyelid Blepharoplasty surgery
Conditions studied
- Eye Disorders — all drugs for Eye Disorders →
Sponsor
Mersin Training and Research Hospital
Who can join
Adults 18 to 80, any sex, with Eye Disorders. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The aim of this study is to compare the effects of two different surgical techniques (Orbicularis Oculi excision and Orbicularis Oculi + Fat excision) applied in upper blepharoplasty surgery on dry eye and to evaluate the effects of these techniques on ocular surface health. 142 patients (71 patients in each group) who met the inclusion and exclusion criteria between 01.05.2025 and 31.12.2025 in Mersin City Education and Research Hospital Eye Diseases Clinic will be included in this study. This study is a prospective, survey study and aims to evaluate the effects of two different surgical techniques (Orbicularis Oculi excision only and Orbicularis Oculi + Fat excision) applied in upper blepharoplasty surgery on postoperative dry eye symptoms. The study will be conducted on patients who are currently scheduled for upper blepharoplasty surgery and no additional surgical procedures or interventions will be applied to the patients. Data collection will be done by a survey study and retrospective recording of routine clinical examinations. The collected data will be used to analyze the differences in dry eye parameters between the two surgical techniques. OSDI scores, BUT times, Oxford staining degrees, Schirmer test results and visual acuity values will be compared at pre- and postoperative time points. Differences between groups will be analyzed by one-tailed independent samples t-test and p\<0.05 will be considered significant. These analyses will be performed to determine the effect of surgical techniques on dry eye symptoms.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
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- PubMed search for NCT06985264
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06985264 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Mersin Training and Research Hospital
- Last refreshed: 22 May 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06985264.
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