NCT06983392

Persistence of Oral DNA Adducts in Smokers and Vapers

Withdrawn NA Last updated 13 February 2026

What this trial tests

NA trial testing Abstain from smoking/vaping in Smokers. Withdrawn.

Timeline

1 March 2026

Primary endpoint
30 July 2029

30 July 2030

Quick facts

Lead sponsor	University of Minnesota
Phase	NA
Status	Withdrawn
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	basic science
Start date	1 March 2026
Primary completion	30 July 2029
Estimated completion	30 July 2030

Drugs / interventions tested

• Abstain from smoking/vaping

Conditions studied

• Smokers — all drugs for Smokers →
• Vaping — all drugs for Vaping →
• Healthy Volunteers — all drugs for Healthy Volunteers →

Sponsor

University of Minnesota

Who can join

21 and older, any sex, with Smokers or Vaping. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study aims to better understand what damage caused to oral cells from smoking and vaping might be important in the formation of oral cancers. We will compare levels of DNA damage between those asked to stop smoking or vaping to those who continue to smoke or vape and those who never use tobacco or nicotine products. The goal is to identify damage that is found at higher levels or remains in the oral cells longer because they might be more important in causing cancer than other types of damage.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.