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NCT06981221
PVI Predictors in Laparoscopic Hysterectomy
trial testing Masimo Radical-7 Pulse Oximeter in Hysterectomy in 50 participants. Completed in 5 May 2025.
30 April 2025
Quick facts
| Lead sponsor | Wonkwang University Hospital |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 50 |
| Start date | 1 April 2025 |
| Primary completion | 30 April 2025 |
| Estimated completion | 5 May 2025 |
| Sites | 1 location across South Korea |
Drugs / interventions tested
- Masimo Radical-7 Pulse Oximeter
Conditions studied
- Hysterectomy — all drugs for Hysterectomy →
- PVI — all drugs for PVI →
- Fluid Responsiveness — all drugs for Fluid Responsiveness →
Sponsor
Wonkwang University Hospital
Who can join
Adults 19 to 70, female only, with Hysterectomy or PVI. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This observational study investigates the predictors of Pleth Variability Index (PVI) changes in euvolemic patients undergoing laparoscopic-assisted vaginal hysterectomy (LAVH). The primary objective is to quantify changes in PVI (ΔPVI) across six intraoperative time points associated with positional shifts. Secondary objectives include identifying key predictors of significant PVI change (ΔPVI ≥ 5%), such as passive leg raising, Trendelenburg position, body mass index (BMI), and intraabdominal pressure. Additional variables including perfusion index, mean arterial pressure, bispectral index, skin temperature, age, and anesthetic agent will be evaluated as potential modulators. Findings aim to support individualized fluid management strategies in LAVH.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06981221
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Wonkwang University Hospital trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06981221 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Wonkwang University Hospital
- Last refreshed: 20 May 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06981221.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing