Who is sponsoring NCT06980688?

NCT06980688 is sponsored by University Hospital, Basel, Switzerland.

What condition does NCT06980688 study?

NCT06980688 studies Anesthesia.

What drugs are being tested in NCT06980688?

Interventions: Propofol titration, Conventional propofol induction.

What is the status of NCT06980688?

NCT06980688 is currently RECRUITING.

Last reviewed 2025-09-12 · How we verify

Multicentre Single-blinded, Expertise-based RCT Comparing Haemodynamic Parameters Between Titration and Conventional Induction of General Anaesthesia With Target-controlled Infusion System in Patients Undergoing Non-cardiac Surgery

NCT06980688 NA RECRUITING

The aim of this multicentre, single-blinded, expertise-based randomised controlled trial is evaluate whether slowly increasing the dose of the anaesthetic drug propofol based on a patient's needs leads to more stable blood pressure compared to giving a standard starting dose in patients aged 55 and older undergoing non-cardiac surgery.

Details

Lead sponsor	University Hospital, Basel, Switzerland
Phase	NA
Status	RECRUITING
Enrolment	320
Start date	2025-09-02
Completion	2027-09

Conditions

Anesthesia

Interventions

Propofol titration
Conventional propofol induction

Primary outcomes

Area under the mean arterial pressure threshold (AUT) — 30 min after start of induction
The area under the mean arterial pressure (MAP)-time curve below each patient's individual baseline MAP (AUT) is measured during the first 30 minutes after the start of anaesthesia induction.

Countries

Switzerland